Results 141 to 150 of about 2,402,623 (312)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2005 This paper explores new working time arrangements around a critique of the ‘commodification of time’ to illuminate the contradictions of such new flexibilities.
Tuckman, A
core
Environment-dependent genetic correlations between development time and body mass in a scorpionfly
, 2007 Engqvist L. Environment-dependent genetic correlations between development time and body mass in a scorpionfly. Zoology. 2007;110(5):344-353.Development time and body mass at maturation are two important fitness traits fundamental for our understanding ...
Engqvist, Leif ; https://orcid.org/
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Application of Intensifying Wind Analysis in Time History Analysis of Tall Buildings
, 2020 Abstract The wind phenomenon has always caused significant damage to structures. Suffering from extensive damage and loss over the years has led researchers to establish the novel science of wind engineering. Wind engineering references introduce wind as an intricate dynamic and random phenomenon and encourage engineers to familiarize themselves ...
openaire +1 more source
, 2005 Maj. Tim Daniel has served with the U.S. Air Force from January of 1983 to the present, as an A-10 Pilot, T-37 Instructor Pilot, an OA-10 Pilot and has 3500 hours of flight time with 100 hours of combat time in Iraq and ...
Daniel, Tim
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Arts and the Aesthetic in Legal History
, 2015 This special issue of Critical Analysis of Law brings together a rich array of articles at the intersections of arts and legal history. In this introduction we reflect on some of the benefits and implications of this interdisciplinary juncture, which ...
Tomlins, Christopher +2 more
core