Results 81 to 90 of about 2,402,623 (312)

Time History Analysis of Irregular Shape Building

open access: yesINTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
Abstract Irregular-shaped buildings have become increasingly common in modern construction due to architectural innovation, yet they pose significant challenges in seismic design because of their complex dynamic behavior. This study investigates the seismic performance of various irregular building configurations L-shaped, C-shaped, T-shaped ...
Hamne A.A Sir   +1 more
openaire   +1 more source

Time use research in Canada – History,critique, perspectives [PDF]

open access: yes
The article examines methodological and substantial problems faced by Canadian time use research. It assesses the gains and the limitations of this research from a historical and comparative perspectives.Canada, time use research, methodology, history ...
Jiri Zuzanek
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Organising through time: Paradox and history

open access: yes
This special issue represents the first effort to bridge paradox theory and historical analysis further. Its goal is to create a fertile environment for advancing the historical study of organisations by contributing to discussions on various research ...
Cunha, MPE   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Event History Analysis of Women's Marriage Timing

open access: yesContemporary Sociological Studies, 1993
本研究の目的は、現代女性の結婚行動を、主として社会階層的要因との関連において説明することである。三二四人の女性の個人データに基づき、結婚を早めたりあるいは遅らせたりする規定要因をイベントヒストリー分析を用いて明らかにする。分析の結果明らかになった知見は、第一に、現代において、女性の結婚の時機は、その出身家庭の社会的地位によっては規定されないこと、つまり結婚の時機を規定するのは、女性本人が形成した社会的地位それ自身である。第二に、学歴や職業といった女性の社会的地位が、結婚の機会や意思決定に影響し、高学歴女性や専門職など高い地位を達成した女性は結婚を遅らせるようになる。第三に、興味深い知見として、母親の就労は娘の結婚年齢を低下させる。
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

PENGARUH PASANGAN DINDING BATA PADA RESPON DINAMIK STRUKTUR GEDUNG AKIBAT BEBAN GEMPA

open access: yesJurnal Teknik Sipil dan Perencanaan, 2016
For analysis purpose, the model system of structure is created as open frame structure rather than massive structure. However, the brick wall will affect to the behavior of the dynamic response when the earthquake induces the structure.
Himawan Indarto   +3 more
doaj  

Home - About - Disclaimer - Privacy