Results 101 to 110 of about 2,402,623 (312)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
International Journal of Coastal and Offshore Engineering, 2020 Significant advantages of FPSO in the ability to transfer and extract from offshore wells have led to their widespread applications. Kind of different modules is installed on the top of these platforms, where one of the major engineering concerns is ...
Mahdi Saleh +2 more
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Analysis of time series data mixed with text
, 2017 In this paper, we present the result of our experiment on analyzing a time series data such as the Nikkei 225 index or foreign currency exchange USD/JPY past data and text corpus related to Japanese economy and finance news or reports.
Part Time Nik Zainun binti Nik Mood
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Seismic performance assessment of knee bracing equipped with shape memory alloys [PDF]
Journal of Structural and Construction Engineering, 2016 According to current seismic design codes, the serviceability of the building is not necessary after the sever earthquakes but the life safety is important. It is caused to reduce the cost of construction.
Mussa Mahmoudi, Sajad Montazeri
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Time History Analysis in Case of a Wind Turbine
, 2013 Due to the extended demands of the sustainability concept a new type of power source was needed at the entire world level. Therefore, in the past decade the wind turbine construction was highly extended. But this aspect came also with special design and building problems, especially in seismic areas.
Olariu, Cerasela-Panseluţa +1 more
openaire +1 more source
, 2005 COL Wilson served with the U.S. Marine Corps (active duty and Reserves) from 1941 to 1977. This interview covers his service in WWII (2nd Marine Division) and briefly his time teaching Combat Intelligence at Quantico, and his years teaching with the ...
Wilson, Tyson
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source