Results 111 to 120 of about 2,402,623 (312)

EVALUATION OF PERFORMANCE OF ASYMMETRICALLY DUAL SYSTEM STRUCTURES USING PUSHOVER AND TIME HISTORY ANALYSES

open access: yesJournal of Civil Engineering
Performance-based design is becoming increasingly popular in designing a seismic resistant building. In the study, a twelvestory, reinforced concrete office building with asymmetric configuration using dual system located in seismic zone 6 was designed ...
Kurdian Suprapto, Sudarto Sudarto
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Remnants of the past, history and the present.

open access: yes, 2004
The article interprets that it is hardly surprising then that philosophers of history point to the slender relationship between the raw facts of the past and understanding the past.
Booth, Douglas
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Visualising Time

open access: yes, 2013
This study investigates the visualisation of temporal relationships between objects. A popular method employed for such information visualisations is the time line consisting of a single horizontal axis along which temporal events or objects are ...
Clarke, Greg
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Studi Perbandingan Analisis Statik dan Dinamik pada Girder Kereta Cepat

open access: yesJurnal Teknik Sipil
Faktor perbesaran dinamis (dynamic amplification factor – DMF) lazim digunakan oleh perencana untuk memperbesar respons struktur (gaya dalam, perpindahan) yang didapatkan dari analisi statis untuk mengakomodasi efek dinamis dari laju kendaraan.
Erwin Lim   +3 more
doaj   +1 more source

Long history, deep time: deepening histories of place

open access: yes, 2015
Overview The vast shape-shifting continent of Australia enables us to take a long view of history. We consider ways to cross the great divide between the deep past and the present.
Mary Anne Jebb, Ann McGrath
core  

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