Results 111 to 120 of about 41,712,769 (261)

Uncovering the Forgotten Roots of Digital History: the Association for History and Computing

, 2023
In recent years, scholars have started to investigate the diverse genealogies of the digital humanities, as part of efforts to consolidate the field by excavating its historical and intellectual underpinnings.
ZAAGSMA, Gerben
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

World War exhibit at Ohio State Museum

, 1940
This photograph shows the "Ohio in the Wars" room at the Ohio State Museum. Seen browsing the exhibit are Dr. William Overman, Curator of History, and Miss Mary Poster, a member of the museum staff.
Ohio History Connection
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ohio Historical Center Doughboy statue

, 1970
This statue of a World War I American soldier by sculptor Bruce Wilder Saville sits on the lawn of the Ohio History Center in Columbus, Ohio. Saville, a professor at The Ohio State University, cast the scuplture, named "The Victorius Doughboy" in 1924 to
Ohio History Connection
core  

Seismic Design and Risk Analyses of Safe-to-Fail Steel and RC Frames for Nuclear Facilities

Jurnal Teknik Sipil
In this article, the design and estimate of the collapse risk of safe-to-fail steel and reinforced concrete (RC) frames due to earthquakes were proposed. The frames are part of nuclear facility buildings, and their failures are to follow the safe-to-fail
Sindur P. Mangkoesoebroto, Shandy Rianto   +1 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Analysis of delay fluctuationsin two-way time transfer earth stations

, 2012
[[abstract]]The delay fluctuations in earth stations have become the main source of instability that degrades the accuracy of two-way satellite time and frequency transfer.
W. H. Tseng;H. T. Lin;P. C. Chang;S. Y. Lin;K. M. Feng
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source