Results 151 to 160 of about 5,546,071 (260)

Time in Therapeutic Range of Unfractionated Heparin-Based Therapy in Critically Ill Patients with COVID-19 Pneumonia

Therapeutics and Clinical Risk Management
Tereza Romanová,1,2 Filip Burša,1,2 Peter Sklienka,1,2 Jiří Sagan,3 Michelle Vaňková,1 Denis Buršík,1,2 Markéta Bílená,1,2 Martin Pulcer,4 Michal Burda,5 Jan Máca1,2,6 1Department of Anesthesiology and Intensive Care Medicine, University ...
Romanová T, Burša F, Sklienka P, Sagan J, Vaňková M, Buršík D, Bílená M, Pulcer M, Burda M, Máca J   +9 more
doaj  

Beyond Time in Range: Hidden Statistical Challenges of Continuous Glucose Monitoring Data in Diabetes Drug Development. [PDF]

J Diabetes Sci Technol
Kim Y, Crackel R, Cho HS, Tu W, Wang Y.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Time in range-A new gold standard in type 2 diabetes research? [PDF]

Diabetes Obes Metab
Goshrani A, Lin R, O'Neal D, Ekinci EI.
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Dermal Glucose Sensing has a Shorter Time Lag Relative to Blood Glucose: Implications for Hypoglycemia Detection and Time in Range. [PDF]

J Diabetes Sci Technol
Ahmad K, Rule P, Bañez B, Hale D, Van Antwerp B.   +4 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Impact of baseline visual acuity, time-in-range and early treatment on functional outcomes in DMO: insights from the IRISS outcomes. [PDF]

Eye (Lond)
Kozak I, Khoramnia R, Taylor SR, Chakravarthy U, ILUVIEN Registry Safety Study (IRISS) Investigators Group.   +4 more
europepmc   +1 more source

Low-Power Wide-Range Time-to-Digital Converter for Time-of-Flight Range Finders

IEEE Access
Ahmed M. Mohey, Marko Kosunen, Jussi Ryynänen, Martin Andraud   +3 more
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source