Results 131 to 140 of about 6,289,366 (311)
Range Unit Root (RUR) Tests: Robust against Nonlinearities, Error Distributions, Structural Breaks and Outliers. [PDF]
Since the seminal paper by Dickey and Fuller in 1979, unit-root tests have conditioned the standard approaches to analysing time series with strong serial dependence in mean behaviour, the focus being placed on the detection of eventual unit roots in an ...
Sipols, Ana E. +2 more
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Frontiers in EndocrinologyObjectivesTo investigate the factors influencing the glucose-lowering efficacy of polyethylene glycol loxenatide (PEG-Loxe) added to diet, exercise, and existing glucose-lowering therapies in patients with poorly controlled type 2 diabetes mellitus (T2DM)
Liye Zhu +11 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Proof of concept of diffuse optical tomography using time-of-flight range imaging cameras
, 2010 Diffuse optical tomography is an optical technique to create 3-dimensional images of the inside of highly scattering material. Research groups around the world have been developing imaging systems using various source-detector arrangements to determine ...
Ahmad Hassan +7 more
core
Neural Network Training for Uncertainty Quantification over Time-Range
, 2022 Traditional uncertainty quantification (UQ) algorithms are mostly developed for a fixed time (term), such as hourly or daily predictions. Although a few UQ techniques can compute UQ over time-range, their quantified uncertainty is usually ever-increasing
D Srinivasan (13467234) +3 more
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Time geography and wildlife home range delineation
, 2014 Funding for this work was provided by Canada’s Natural Science and Engineering Research Council (NSERC) and GEOIDE through the Government of Canada’s Networks of Centres of Excellence program.We introduce a new technique for delineating animal home ...
Long, J.A., Nelson, T.A.
core +1 more source