Results 121 to 130 of about 1,461,021 (294)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Deep Learning-Based Location Spoofing Attack Detection and Time-of-Arrival Estimation through Power Received in IoT Networks. [PDF]
Sensors (Basel), 2023 Aldosari W.
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Risk of psychosis among migrants to the Netherlands by time since arrival. [PDF]
Psychol Med, 2023 Termorshuizen F, Selten JP.
europepmc +1 more source
Timing of the Crab pulsar. I - Arrival times.
The Astrophysical Journal Supplement Series, 1975 This paper presents the pulse arrival times obtained during five years of observation of the Crab Nebula pulsar, PSR 0531+21. The reduction from topocentric to barycentric arrival times and errors affecting the results are discussed. Subsequent papers in this series will use these data to determine the time dependence of the pulse frequency. (AIP)
openaire +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Time-of-Arrival Offset Estimation in Neural Network Atomic Denoising in Wireless Location. [PDF]
Sensors (Basel), 2022 Hu Y, Peng A, Tang B, Ou G, Lu X.
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Evaluation of 5G Positioning Based on Uplink SRS and Downlink PRS Under LOS and NLOS Environments
Applied SciencesThe evolution of 5G technology has led to significant advancements in high-accuracy positioning. However, the actual performance of 5G signals for user equipment (UE) positioning has not been thoroughly examined, especially under varying propagation ...
Syed Shahid Shah +6 more
doaj +1 more source