Results 101 to 110 of about 271,289 (267)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Evaluation of 5G Positioning Based on Uplink SRS and Downlink PRS Under LOS and NLOS Environments

Applied Sciences
The evolution of 5G technology has led to significant advancements in high-accuracy positioning. However, the actual performance of 5G signals for user equipment (UE) positioning has not been thoroughly examined, especially under varying propagation ...
Syed Shahid Shah, Chao Sun, Dongkai Yang, Muhammad Wisal, Yingzhe He, Bai Lu, Ying Xu   +6 more
doaj   +1 more source

Vehicle Localization Using Doppler Shift and Time of Arrival Measurements in a Tunnel Environment. [PDF]

Sensors (Basel), 2022
Halili R, BniLam N, Yusuf M, Tanghe E, Joseph W, Weyn M, Berkvens R.   +6 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Deep Learning Approaches for Robust Time of Arrival Estimation in Acoustic Emission Monitoring. [PDF]

Sensors (Basel), 2022
Zonzini F, Bogomolov D, Dhamija T, Testoni N, De Marchi L, Marzani A.   +5 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Non-Line-of-Sight Ultraviolet Positioning via Time Difference of Arrival

IEEE Open Journal of the Communications Society
For challenging environments where conventional line-of-sight (LOS) systems are not available, we propose a novel non-line-of-sight (NLOS) ultraviolet (UV) positioning system based on time difference of arrival (TDOA).
Shihui Yu, Lingfeng Li, Yuchen Pan, Juliang Cao, Ruihang Yu, Chen Gong, Zhengyuan Xu   +6 more
doaj   +1 more source

The Life Satisfaction of Immigrants in Canada: Does Time Since Arrival Matter more than Income? [PDF]

J Int Migr Integr, 2022
Monteiro L, Haan M.
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source