Results 91 to 100 of about 166,620,327 (288)

Geometrical statistical channel model with an Inverted-Parabolic spatial distribution

open access: yesTongxin xuebao, 2014
Due to the complexity of calculation for the parameters of angle of arrival(AOA),time of arrival(TOA) and Dopplerspectra(DS),etc.,a proper geometrical statistical channel model was proposed with inverted-parabolic spatial distribution around mobile ...
Jie ZHOU, Dong-dong XU, Kikuchi HISAKAZU
doaj  

Phase Difference of Arrival Aided Downlink Time Difference of Arrival Ultra-Wide Band Positioning System

open access: yesIEEE Access
Currently there is a growing demand for accurate and reliable positioning indoors or in other environments, where Global Navigation Satellite Systems (GNSS) are unavailable.
Josef Krska   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Variants of the Arrival problem [PDF]

open access: yes
Arrival is a decision problem with, as yet, neither a known polynomial time algorithm nor a P-hardness result. The natural witness-search problem for Arrival also lies in many interesting sub-classes of TFNP. In this thesis, we will explore further the
Webster, Thomas
core   +1 more source

Root-MUSIC-based joint TOA and DOA estimation in IR-UWB

open access: yesTongxin xuebao, 2014
The parameters can be estimated via two-dimensional (2D) multiple signal classification (MUSIC) algorithm, in which the two-dimensional spectral peak searching, however, requires much higher computational complexity.
Fang-qiu WANG, Xiao-fei ZHANG, Fei WANG
doaj   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Updating Measures of CME Arrival Time Errors

open access: yesSpace Weather
Coronal mass ejections (CMEs) drive space weather effects at Earth and the heliosphere. Predicting their arrival is a major part of space weather forecasting.
C. Kay   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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