Results 81 to 90 of about 339,040 (317)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
On identifiability of MAP processes [PDF]
, 2008 Two types of transitions can be found in the Markovian Arrival process or MAP: with and without arrivals. In transient transitions the chain jumps from one state to another with no arrival; in effective transitions, a single arrival occurs.
Lillo Rodríguez, Rosa Elvira +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2007 The central detector of the KASCADE experiment is equipped with a trigger and timing facility, which enables measurements of the arrival time distributions of muons hitting the central detector.
M. Foller +2 more
core
Time to arrival by mode of arrival.
, 2019 Time to arrival by mode of arrival.
Hannah Janeway (7037423) +4 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Research of Batch Scheduling with Arrival Time Based on Estimation of Distribution Algorithm
, 2014 Estimation of distribution has been used to solve the batch scheduling problem with job release problem, which minimizing the make span as the objective function.
Xiaofeng Zhou +7 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Swapped Sectors Detection Based on User Location During Inter-Site Handovers
IEEE Access, 2019 Network roll-out is a process composed of several actions, which, if not completed correctly, may degrade the final system performance. A common error during the roll-out process is the case in which feeders from baseband units to radio units or feeders ...
Omar Kaddoura +3 more
doaj +1 more source