Results 81 to 90 of about 1,461,021 (294)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A Deep Learning Approach to Position Estimation from Channel Impulse Responses

Sensors, 2019
Radio-based locating systems allow for a robust and continuous tracking in industrial environments and are a key enabler for the digitalization of processes in many areas such as production, manufacturing, and warehouse management.
Arne Niitsoo, Thorsten Edelhäußer, Ernst Eberlein, Niels Hadaschik, Christopher Mutschler   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Constrained Weighted Least-Squares Algorithms for 3-D AOA-Based Hybrid Localization

IEEE Open Journal of Signal Processing
Source localization with time-of-arrival (TOA), time-difference-of-arrival (TDOA), time-delay (TD), received-signal-strength (RSS), or angle-of-arrival (AOA) measurements from several spatially distributed sensors is commonly used in practice.
Yanbin Zou, Wenbo Wu, Jingna Fan, Huaping Liu   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Transition from discrete to continuous time of arrival distribution for a quantum particle

, 2005
We show that the Kijowski distribution for time of arrivals in the entire real line is the limiting distribution of the time of arrival distribution in a confining box as its length increases to infinity.
A. Peres, E. A. Galapon, Eric A. Galapon, F. Delgado, I. L. Egusquiza, Iñigo Egusquiza, J. Gonzalo Muga, J. Kijowski, M. Jammer, P. Busch, P. R. Holland, Ph. Blanchard, W. Pauli   +12 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Quantum optical time-of-arrival model in three dimensions

, 2004
We investigate the three-dimensional formulation of a recently proposed operational arrival-time model. It is shown that within typical conditions for optical transitions the results of the simple one-dimensional version are generally valid.
Aharonov Y, Allcock G R, Blanchard P, Carmichael H, Damborenea J A, Damborenea J A, G C Hegerfeldt, Galapon E A, Giannitrapani R, Halliwell J J, Hegerfeldt G C, Hegerfeldt G C, Hegerfeldt G C, Hegerfeldt G C Wilser T S H D Doebner W Scherer F Schroeck, J G Muga, Kijowski J, Kocha?ski P, Leavens C R, León J, Muga J G, Navarro B, Navarro B, Ruschhaupt A, Ruschhaupt A, V Hannstein, Werner R   +25 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Two Stages of Arrival Aircraft: Influencing Factors and Prediction of Integrated Arrival Time

Aerospace
To enhance the accuracy and real-time capability of estimated in-block time (EIBT) predictions at airports, this study proposes a two-stage integrated prediction method.
Xiaowei Tang, Mengfan Ye, Jiaqi Wu, Shengrun Zhang   +3 more
doaj   +1 more source