Results 71 to 80 of about 339,040 (317)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Model on Indoor Localization System Based on the Time Difference Without Synchronization

open access: yesIEEE Access, 2018
Localization has emerged as an attractive solution to enable new business models that rely on location-based services in wireless networks for communication, sensing, and control. In particular, time difference-of-arrival (TDOA) is one of the widely used
Yuan Xue   +4 more
doaj   +1 more source

On the Sources and Sizes of Uncertainty in Predicting the Arrival Time of Interplanetary Coronal Mass Ejections Using Global MHD Models

open access: yesSpace Weather, 2021
Accurate predictions of the properties of interplanetary coronal mass ejection (ICME)‐driven disturbances are a key objective for space weather forecasts.
Pete Riley, Michal Ben‐Nun
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Self-Calibration for the Time Difference of Arrival Positioning

open access: yesSensors, 2020
The time-difference-of-arrival (TDOA) self-calibration is an important topic for many applications, such as indoor navigation. One of the most common methods is to perform nonlinear optimization.
Juri Sidorenko   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Two Stages of Arrival Aircraft: Influencing Factors and Prediction of Integrated Arrival Time

open access: yesAerospace
To enhance the accuracy and real-time capability of estimated in-block time (EIBT) predictions at airports, this study proposes a two-stage integrated prediction method.
Xiaowei Tang   +3 more
doaj   +1 more source

A Deep Learning Approach to Position Estimation from Channel Impulse Responses

open access: yesSensors, 2019
Radio-based locating systems allow for a robust and continuous tracking in industrial environments and are a key enabler for the digitalization of processes in many areas such as production, manufacturing, and warehouse management.
Arne Niitsoo   +4 more
doaj   +1 more source

The solution to the problem of time in quantum gravity also solves the time of arrival problem in quantum mechanics

open access: yesNew Journal of Physics, 2022
We introduced with coauthors some years ago a solution to the problem of time in quantum gravity which consists in formulating the quantum theory in terms of real clocks.
Rodolfo Gambini, Jorge Pullin
doaj   +1 more source

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