Results 161 to 170 of about 339,040 (317)
Noise resistant method for cardiac pulse wave arrival time estimation /
, 2014 Pulse arrival time is the time interval which is needed for pulse wave to travel the distance from the heart to some distal place on the body. Almost all definitions of pulse arrival time estimation are based on high quality photoplethysmogram signals ...
Rapalis, A., +7 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 1999 We propose a covariant algorithm for relativistic ideal measurements and for relativistic continuous measurements, its non-relativistic limit results the algorithm of the Event-Enhanced Quantum Theory. Therefore an additional intrinsic parameter, the proper time, is used.
openaire +2 more sources
Visual Perception and Analysis of an Approaching Train at Railway Level Crossings in New Zealand
, 2010 The prevalence of railway level crossing accidents in New Zealand is a high profile issue that has warranted close scrutiny over the last 10 years. However, the incident rate has not decreased. This research examined the possibility that visual illusions
Clark, Helen Elizabeth
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Traffic congestion prediction based on Estimated Time of Arrival. [PDF]
PLoS One, 2020 Zafar N, Ul Haq I.
europepmc +1 more source
Pondering Hierarchy of Oppressions in Australia: The Case of Refugees and Their Mode of Arrival
, 2019 This paper is inspired by a conversation about the differences in treatment of refugees in Australia depending on their mode of arrival. The circumstances for seeking asylum are similar—displacement, forced migration, fight/fleeing for survival, hope for
Ramos, Fabiane
core