Results 91 to 100 of about 3,595,948 (318)
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
The variational calculus on time scales [PDF]
15 pages; Published in: Int. J. Simul. Multidisci. Des. Optim.
openaire +4 more sources
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Kinematical Relativity and the Geological Time-Scale [PDF]
G. J. Whitrow
openalex +1 more source
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Oscillation of second order neutral dynamic equations with distributed delay
In this paper, we establish new oscillation criteria for second order neutral dynamic equations with distributed delay by employing the generalized Riccati transformation.
Qiaoshun Yang, Zhiting Xu, Ping Long
doaj +1 more source
A Flow Model and a Time Scale for the Ice Core from Camp Century, Greenland [PDF]
W. Dansgaard, S. J. Johnsen
openalex +1 more source
Hamiltonian Systems on Time Scales
The authors investigate linear Hamiltonian systems on time scales \[ x^{\Delta }={\mathcal H}(t)x, \] where \({}^{\Delta }\) denotes the generalized (time scale) derivative, \(x\in \mathbb{R}^{2n}\), \({\mathcal H}\) is a \(2n\times 2n\) matrix satisfying \({\mathcal H}^*(t){\mathcal J}+{\mathcal J}{\mathcal H}(t)+ \mu(t){\mathcal H}^*(t){\mathcal J ...
Jerry Ridenhour +2 more
openaire +3 more sources
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source

