Results 91 to 100 of about 11,420,922 (288)
Oscillation of second order neutral dynamic equations with distributed delay
Electronic Journal of Qualitative Theory of Differential Equations, 2016 In this paper, we establish new oscillation criteria for second order neutral dynamic equations with distributed delay by employing the generalized Riccati transformation.
Qiaoshun Yang, Zhiting Xu, Ping Long
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Oscillatory behavior of higher-order neutral type dynamic equations
Electronic Journal of Qualitative Theory of Differential Equations, 2013 The oscillation behavior of solutions for higher-order delay dynamic equations of neutral type is investigated by making use of comparison with second-order dynamic equations.
Said Grace, Raziye Mert, Agacik Zafer
doaj +1 more source
Universality of trap models in the ergodic time scale [PDF]
, 2012 Consider a sequence of possibly random graphs $G_N=(V_N, E_N)$, $N\ge 1$, whose vertices's have i.i.d. weights $\{W^N_x : x\in V_N\}$ with a distribution belonging to the basin of attraction of an $\alpha$-stable law ...
Jara, M., Landim, C., Teixeira, A.
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Conditional oscillation of half-linear Euler-type dynamic equations on time scales
Electronic Journal of Qualitative Theory of Differential Equations, 2015 We investigate second-order half-linear Euler-type dynamic equations on time scales with positive periodic coefficients. We show that these equations are conditionally oscillatory, i.e., there exists a sharp borderline (a constant given by the ...
Petr Hasil, J. Vítovec
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
New results for time reversed symplectic dynamic systems and quadratic functionals
Electronic Journal of Qualitative Theory of Differential Equations, 2012 In this paper, we examine time scale symplectic (or Hamiltonian) systems and the associated quadratic functionals which contain a forward shift in the time variable.
Roman Simon Hilscher, Petr Zemanek
doaj +1 more source
Scale invariance in financial time series [PDF]
We focus on new insights of scale invariance and scaling properties usefully applied in the framework of a statistical approach to study the empirical finance.
Ranasinghe Malmini
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source