Results 181 to 190 of about 11,323,677 (336)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Shifting Scales of Time and Space: Establishing Connections Across the Humanities [PDF]

, 2016
Tharuka Prematillake Thibbotuwawa
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Reverse Time-to-Death as Time-Scale in Time-to-Event Analysis for Studies of Advanced Illness and Palliative Care. [PDF]

Stat Med
Cheung YB, Ma X, Chaudhry I, Liu N, Zhuang Q, Yang GM, Malhotra C, Finkelstein EA.   +7 more
europepmc   +1 more source

Evidence of cospeciation between termites and their gut bacteria on a geological time scale. [PDF]

Proc Biol Sci, 2023
Arora J, Buček A, Hellemans S, Beránková T, Arias JR, Fisher BL, Clitheroe C, Brune A, Kinjo Y, Šobotník J, Bourguignon T.   +10 more
europepmc   +1 more source

BRITE-Constellation high-precision time-dependent photometry of the early O-type supergiant ζ Puppis unveils the photospheric drivers of its small- and large-scale wind structures [PDF]

, 2017
Tahina Ramiaramanantsoa, A. F. J. Moffat, Robert O. Harmon, Richard Ignace, Nicole St‐Louis, D. Vanbeveren, T. Shenar, H. Pablo, Noel D. Richardson, Ian D. Howarth, I. R. Stevens, Caroline Piaulet, Lucas St-Jean, Thomas Eversberg, A. Pigulski, Adam Popowicz, R. Kuschnig, E. Zocłońska, B. Buysschaert, G. Handler, W. W. Weiß, G. A. Wade, S. M. Ruciński, K. Zwintz, P. Luckas, B. Heathcote, P. Cacella, Jonathan Powles, Malcolm Locke, T. Bohlsen, André-Nicolas Chené, B. Miszalski, W. L. Waldron, M. Kotze, Enrico J. Kotze, T. Böhm   +35 more
openalex   +1 more source

Asymptotic behavior of a low-temperature non-cascading 2-GREM dynamics at extreme time scales

, 2022
Luiz Renato Fontes, Susana Frómeta, Leonel Zuaznábar   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Fluorescence-Based Temperature-Jump Apparatus for Illustrating Protein Dynamics on the Millisecond Time Scale. [PDF]

Anal Chem
Kung LC, Chu LK.
europepmc   +1 more source

Rapid memory encoding in a recurrent network model with behavioral time scale synaptic plasticity. [PDF]

PLoS Comput Biol, 2023
Li PY, Roxin A.
europepmc   +1 more source