Results 81 to 90 of about 11,323,677 (336)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

On the existence and uniqueness of solution to Volterra equation on a time scale

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
Using a global inversion theorem we investigate properties of the following ...
Kluczyński Bartłomiej
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Evolution of Bulk Scale Factor in Warped Space-time [PDF]

, 2012
In this work the role of extra dimensions in the accelerated universe through the scenario of higher-dimensional Friedmann-Robertson-Walker (FRW) cosmology has been studied. For this purpose, we first consider warped space-time in the standard flat brane
Mohsenzadeh, M., Yusofi, E.
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Nabla derivatives associated with nonlinear control systems on homogeneous time scales

Nonlinear Analysis, 2016
The backward shift and nabla derivative operators, defined by the control system on homogeneous time scale, in vector spaces of one-forms and vector fields are introduced and some of their properties are proven.
Zbigniew Bartosiewicz, Ülle Kotta, Tanel Mullari, Maris Tõnso, Ewa Pawluszewicz, Małgorzata Wyrwas   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Integration on time scales

Journal of Mathematical Analysis and Applications, 2003
In this paper, the author defines the Riemann and Lebesgue integrals (more precisely, the Riemann and Lebesgue \(\Delta\)-integrals and \(\nabla\)-integrals) on time scales and studies their properties and relationship. In particular, the author presents results concerning the lower and upper Darboux sums, the Riemann sums, the Riemann and Lebesgue ...
openaire   +1 more source

Scale invariance in financial time series [PDF]

We focus on new insights of scale invariance and scaling properties usefully applied in the framework of a statistical approach to study the empirical finance.
Ranasinghe Malmini
core