Results 121 to 130 of about 810,476 (239)

'Ion-freeze' efficiency in perovskite solar cells: time scales for ion immobilization. [PDF]

EES Solar
H Balaguera E, Marinelli Pra FJ, Das C, Torresani L, Bisquert J, Saliba M.   +5 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Time Scales of Gaseous Smoke Contamination Indoors from Real and Simulated Wildland-Urban Interface Fires. [PDF]

ACS EST Air
Link MF, Davis AY, Lima NM, Falkenstein-Smith RL, Robertson RL, Cleary TG, Emmerich S, Poppendieck D.   +7 more
europepmc   +1 more source

Marine reserves promote cycles in fish populations on ecological and evolutionary time scales. [PDF]

Proc Natl Acad Sci U S A, 2023
Chen R, Chaparro-Pedraza PC, Xiao S, Jia P, Liu QX, de Roos AM.   +5 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Postsynaptic frequency filters shaped by the interplay of synaptic short-term plasticity and cellular time scales. [PDF]

J Comput Neurosci
Mondal Y, Benito GV, Pena RFO, Rotstein HG.   +3 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Temperature-dependent trapping and polaron annihilation on ultrafast time scales in metal-halide perovskites. [PDF]

J Phys Chem Lett
Wang J, Park J, Gao L, Virgilio LD, Qu S, Kim H, Wang HI, Wu LL, Zeng W, Bonn M, Ren Z, Geuchies JJ.   +11 more
europepmc   +1 more source

Time Scales and Moments of Listening Effort Revealed in Pupillometry. [PDF]

Semin Hear, 2023
Winn MB.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source