Results 161 to 170 of about 3,286,410 (288)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Postsynaptic frequency filters shaped by the interplay of synaptic short-term plasticity and cellular time scales. [PDF]

J Comput Neurosci
Mondal Y, Benito GV, Pena RFO, Rotstein HG.   +3 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Temperature-dependent trapping and polaron annihilation on ultrafast time scales in metal-halide perovskites. [PDF]

J Phys Chem Lett
Wang J, Park J, Gao L, Virgilio LD, Qu S, Kim H, Wang HI, Wu LL, Zeng W, Bonn M, Ren Z, Geuchies JJ.   +11 more
europepmc   +1 more source

Time Scales and Moments of Listening Effort Revealed in Pupillometry. [PDF]

Semin Hear, 2023
Winn MB.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Smooth Hazards With Multiple Time Scales. [PDF]

Stat Med
Carollo A, Eilers P, Putter H, Gampe J.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Fibrin/MoS₂-nanosheet conductive hydrogels with programmed time scales and pathways for bioresorption. [PDF]

Nanoscale Adv
Shukla V, Bilderback WT, Fernandes D, Daley M, Basnet R, Joshi P, Yang Z, Tripathi A, Rosenstein JK, Coulombe K, Hurt RH.   +10 more
europepmc   +1 more source

Dynamics and Time Scales of Higher-Order Correlations in Supercooled Colloidal Systems. [PDF]

J Phys Chem Lett, 2023
Striker NN, Lokteva I, Dartsch M, Dallari F, Goy C, Westermeier F, Markmann V, Hövelmann SC, Grübel G, Lehmkühler F.   +9 more
europepmc   +1 more source