Results 71 to 80 of about 8,095,148 (356)
This data manuscript presents a set of signals collected from the Llaima volcano located at the western edge of the Andes in Araucania Region, Chile. The signals were recorded from the LAV station between 2010 and 2016.
João Paulo Canário +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A time series analysis of 871 543 pediatric emergency visits revealed that the coronavirus disease 2019 (COVID-19) lockdown and school closures were associated with a significant decrease in infectious diseases disseminated through airborne or fecal-oral
F. Angoulvant +12 more
semanticscholar +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Wavelet analysis of covariance with application to atmospheric time series
Multiscale analysis of univariate time series has appeared in the literature at an ever increasing rate. Here we introduce the multiscale analysis of covariance between two time series using the discrete wavelet transform.
Whitcher, Brandon +2 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
An Approach to Time Series Analysis
It may fairly be said that modern time series analysis is a subject which embraces three fields which while closely related have tended to develop somewhat independently. These fields are (i) statistical communication and control theory, (ii) the probabilistic (and Hilbert space) theory of stochastic processes processing finite second moments, and (iii)
openaire +3 more sources
Flexible Time Series Analysis [PDF]
In this chapter we present nonparametric methods and available quantlets for nonlinear modelling of univariate time series. A general nonlinear time series model for an univariate stochastic process Y t t=1 T is given by the heteroskedastic nonlinear autoregressive (NAR) process $${Y_t} = f\left( {{Y_{t - i1}},{Y_{t - i2}}, \ldots ,{Y_{t - im ...
Härdle, Wolfgang, Tschernig, Rolf
openaire +5 more sources
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

