Results 91 to 100 of about 2,530,237 (313)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Time-series analysis of varve thickness data [PDF]

open access: yes, 2019
This data package comprises two datasets. 1) Time-series analysis of glacial varve thickness data from Lago General Carrera (Chile)–Buenos Aires (Argentina) in Patagonia, southern South America.
Jacob Bendle (6284315)   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Topological Time Series Analysis

open access: yesNotices of the American Mathematical Society, 2019
Time series are ubiquitous in our data rich world, Jose A Perea describes how ideas from dynamical systems and topological data analysis can be combined to gain insights from time-varying data.
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Complexity Analysis of Environmental Time Series

open access: yesEntropy
Small, forested catchments are prototypes of terrestrial ecosystems and have been studied in several disciplines of environmental science over several decades.
Holger Lange, Michael Hauhs
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Nonparametric frequency domain analysis of nonstationary multivariate time series [PDF]

open access: yes, 2002
We analyse the properties of nonparametric spectral estimates when applied to long memory and trending nonstationary multiple time series. We show that they estimate consistently a generalized or pseudo-spectral density matrix at frequencies both close ...
Velasco Gómez, Carlos   +2 more
core   +1 more source

Univariant time series analysis applied to ozone forecasting in the city of Cali, Colombia

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2014
The modelling results of tropospheric ozone concentration in the urban area of Cali, Colombia, suitable for short term forecasting, are presented. Results were obtained by using an univariate time series analysis.
Mauricio Jaramillo Ayerbe   +4 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

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