Results 101 to 110 of about 8,095,148 (356)

TATS: toolbox for time series data augmentation [PDF]

open access: yesPeerJ Computer Science
Augmenting time series data plays a crucial role in enhancing the generalization of classification models, especially in scenarios where labeled datasets are limited.
Dawid Warchoł, Mariusz Oszust
doaj   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Anomaly Detection Algorithm Using a Hybrid Modelling Approach for Energy Consumption Time Series

open access: yes, 2023
1930Many energy time series captured by real-time systems contain errors or anomalies that prevent accurate forecasts of time series evolution. However, accurate forecasting of load time series and fluctuating renewable energy feed-in as well as ...
Lenk, Steve   +5 more
core   +1 more source

Complexity Analysis of Environmental Time Series

open access: yesEntropy
Small, forested catchments are prototypes of terrestrial ecosystems and have been studied in several disciplines of environmental science over several decades.
Holger Lange, Michael Hauhs
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On Consistency in Time Series Analysis

open access: yesThe Annals of Statistics, 1978
A number of statistics that arise in time series analysis can be represented as the sum of a partial realization of a possibly serially dependent and nonstationary discrete-parameter stochastic process. The almost sure and $L_p, p > 1$, convergence of such statistics is investigated, under various moment conditions. The results are applied to the least
openaire   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Statistical analysis of functional time series

open access: yes, 2012
info:eu-repo/semantics ...
Hörmann, Siegfried
core  

Nonparametric frequency domain analysis of nonstationary multivariate time series [PDF]

open access: yes, 2002
We analyse the properties of nonparametric spectral estimates when applied to long memory and trending nonstationary multiple time series. We show that they estimate consistently a generalized or pseudo-spectral density matrix at frequencies both close ...
Velasco Gómez, Carlos   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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