Results 81 to 90 of about 7,974,129 (270)

Bayesian time series analysis of terrestrial impact cratering

, 2011
Giant impacts by comets and asteroids have probably had an important influence on terrestrial biological evolution. We know of around 180 high velocity impact craters on the Earth with ages up to 2400Myr and diameters up to 300km.
Alvarez, Alvarez, Alvarez, Bahcall, Bailer-Jones, Berger, Berger, Broadbent, C. A. L. Bailer-Jones, Chang, Christensen, Davis, Deutsch, Gardner, Gregory, Grieve, Grieve, Grieve, Grieve, Hallam, Heisler, Jaynes, Jeffreys, Jetsu, Kass, Le Feuvre, Lyytinen, Mackay, Marden, Matsumoto, McEwen, Montanari, Napier, Napier, Rampino, Shoemaker, Shuter, Stigler, Stigler, Stothers, Torbett, Wickramasinghe, Yabushita, Yabushita, Yabushita   +44 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Time averaging, ageing and delay analysis of financial time series

New Journal of Physics, 2017
We introduce three strategies for the analysis of financial time series based on time averaged observables. These comprise the time averaged mean squared displacement (MSD) as well as the ageing and delay time methods for varying fractions of the ...
Andrey G Cherstvy, Deepak Vinod, Erez Aghion, Aleksei V Chechkin, Ralf Metzler   +4 more
doaj   +1 more source

Detection of time reversibility in time series by ordinal patterns analysis

, 2018
Time irreversibility is a common signature of nonlinear processes, and a fundamental property of non-equilibrium systems driven by non-conservative forces.
Chavez, Mario, Herrera-Diestra, José L., Martínez, Johann H.   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Univariant time series analysis applied to ozone forecasting in the city of Cali, Colombia

Revista Facultad de Ingeniería Universidad de Antioquia, 2014
The modelling results of tropospheric ozone concentration in the urban area of Cali, Colombia, suitable for short term forecasting, are presented. Results were obtained by using an univariate time series analysis.
Mauricio Jaramillo Ayerbe, Daniel Enrique González Gómez, María Eugenia Núñez Cabrera, Gloria Esperanza Portilla, Jesús Heriberto Lucio García   +4 more
doaj   +1 more source

Analysis of Break-Points in Financial Time Series [PDF]

, 2016
A time series is a set of random values collected at equal time intervals; this randomness makes these types of series not easy to predict because the structure of the series may change at any time.
Habimana, Jean Remy
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Deep Learning for Anomaly Detection in Time-Series Data: An Analysis of Techniques, Review of Applications, and Guidelines for Future Research

IEEE Access
Industries are generating massive amounts of data due to increased automation and interconnectedness. As data from various sources becomes more available, the extraction of relevant information becomes crucial for understanding complex systems’ ...
Usman Ahmad Usmani, Izzatdin Abdul Aziz, Jafreezal Jaafar, Junzo Watada   +3 more
doaj   +1 more source