Results 41 to 50 of about 339,262 (287)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Temporal network analysis using zigzag persistence

open access: yesEPJ Data Science, 2023
This work presents a framework for studying temporal networks using zigzag persistence, a tool from the field of Topological Data Analysis (TDA). The resulting approach is general and applicable to a wide variety of time-varying graphs.
Audun Myers   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Nonlinear time-series analysis revisited

open access: yes, 2015
In 1980 and 1981, two pioneering papers laid the foundation for what became known as nonlinear time-series analysis: the analysis of observed data---typically univariate---via dynamical systems theory.
Bradley, Elizabeth, Kantz, Holger
core   +1 more source

Persistence and Stochastic Periodicity in the Intensity Dynamics of a Fiber Laser During the Transition to Optical Turbulence [PDF]

open access: yes, 2018
Many natural systems display transitions among different dynamical regimes, which are difficult to identify when the data is noisy and high dimensional.
Carpi, Laura, Masoller, Cristina
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Can Recurrence Quantification Analysis Be Useful in the Interpretation of Airborne Turbulence Measurements?

open access: yesGeophysical Research Letters
In airborne data or model outputs, clouds are often defined using information about Liquid Water Content (LWC). Unfortunately LWC is not enough to retrieve information about the dynamical boundary of the cloud, that is, volume of turbulent air around the
Stanisław Król   +5 more
doaj   +1 more source

Explicit Construction of First Integrals with Quasi-monomial Terms from the Painlev\'{e} Series [PDF]

open access: yes, 2004
The Painlev\'{e} and weak Painlev\'{e} conjectures have been used widely to identify new integrable nonlinear dynamical systems. For a system which passes the Painlev\'{e} test, the calculation of the integrals relies on a variety of methods which are ...
Bountis, Tassos   +2 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Estimation of Power System Inertia Using Nonlinear Koopman Modes

open access: yes, 2018
We report a new approach to estimating power system inertia directly from time-series data on power system dynamics. The approach is based on the so-called Koopman Mode Decomposition (KMD) of such dynamic data, which is a nonlinear generalization of ...
Hamasaki, Ryo   +2 more
core   +1 more source

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