Results 71 to 80 of about 339,262 (287)

Extracting interpretable signatures of whole-brain dynamics through systematic comparison.

PLoS Computational Biology
The brain's complex distributed dynamics are typically quantified using a limited set of manually selected statistical properties, leaving the possibility that alternative dynamical properties may outperform those reported for a given application.
Annie G Bryant, Kevin Aquino, Linden Parkes, Alex Fornito, Ben D Fulcher   +4 more
doaj   +1 more source

Shape Distributions of Nonlinear Dynamical Systems for Video-based Inference

, 2016
This paper presents a shape-theoretic framework for dynamical analysis of nonlinear dynamical systems which appear frequently in several video-based inference tasks.
Turaga, Pavan, Venkataraman, Vinay
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Exploring recursive properties and dynamical complexity in scalar time-series using threshold-free recursive analysis approach

AIP Advances
In this project, a threshold-free recursive analysis approach was investigated to reveal the recursive properties of dynamic systems. Specifically, the occurrence of recurrent patterns in phase trajectory was identified by a threshold-free recursive ...
Guodong Sun, Haisheng Wang, Yuting Wang, Bobo Jian   +3 more
doaj   +1 more source

Analysis and prediction of hydrometeorological time series by dynamical system approach

, 2012
published_or_final_version ; Civil Engineering ; Doctoral ; Doctor of ...
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Granger causality network reconstruction of conductance-based integrate-and-fire neuronal systems. [PDF]

PLoS ONE, 2014
Reconstruction of anatomical connectivity from measured dynamical activities of coupled neurons is one of the fundamental issues in the understanding of structure-function relationship of neuronal circuitry. Many approaches have been developed to address
Douglas Zhou, Yanyang Xiao, Yaoyu Zhang, Zhiqin Xu, David Cai   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Autoencoding for the "Good Dictionary" of eigenpairs of the Koopman operator

AIMS Mathematics
Reduced order modelling relies on representing complex dynamical systems using simplified modes, which can be achieved through the Koopman operator(KO) analysis.
Neranjaka Jayarathne, Erik M. Bollt
doaj   +1 more source