Results 81 to 90 of about 397,119 (307)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Earthquake magnitude prediction based on artificial neural networks: A survey

Croatian Operational Research Review, 2016
The occurrence of earthquakes has been studied from many aspects. Apparently, earthquakes occur without warning and can devastate entire cities in just a few seconds, causing numerous casualties and huge economic loss.
Emilio Florido, José L. Aznarte, Antonio Morales-Esteban, Francisco Martínez-Álvarez   +3 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

DeepONet-Inspired Architecture for Efficient Financial Time Series Prediction

Mathematics
Financial time series prediction is a fundamental problem in investment and risk management. Deep learning models, such as multilayer perceptrons, Convolutional Neural Networks (CNNs), and Long Short-Term Memory (LSTM), have been widely used in modeling ...
Zeeshan Ahmad, Shudi Bao, Meng Chen
doaj   +1 more source

Assessment and prediction of road accident injuries trend using time-series models in Kurdistan

Burns & Trauma, 2018
Background Road traffic accidents are commonly encountered incidents that can cause high-intensity injuries to the victims and have direct impacts on the members of the society. Iran has one of the highest incident rates of road traffic accidents.
Maryam Parvareh, Asrin Karimi, Satar Rezaei, Abraha Woldemichael, Sairan Nili, Bijan Nouri, Nader Esmail Nasab   +6 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

CNN-Based Time Series Decomposition Model for Video Prediction

IEEE Access
Video prediction presents a formidable challenge, requiring effectively processing spatial and temporal information embedded in videos. While recurrent neural network (RNN) and transformer-based models have been extensively explored to address spatial ...
Jinyoung Lee, Gyeyoung Kim
doaj   +1 more source

Time Series Prediction : Predicting Stock Price

, 2017
Under advisement of Dr. Sang Kim, for his class CS542.
Elliot, Aaron, Hsu, Cheng Hua
openaire   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source