Results 91 to 100 of about 2,310,152 (342)

Understanding patient perspectives on management of their chronic pain: online survey protocol

open access: yesJournal of Pain Research, 2016
Manasi Gaikwad,1,2 Simon Vanlint,1 G Lorimer Moseley,2,3 Murthy N Mittinty,4 Nigel Stocks1 1Discipline of General Practice, School of Medicine, University of Adelaide, Adelaide, SA, 2Sansom Institute for Health Research, University of South Australia ...
Gaikwad M   +4 more
doaj  

Optimal Time to Ship Human Islets Post Tissue Culture to Maximize Islet Recovery

open access: yesCell Transplantation, 2020
Access to functional high-quality pancreatic human islets is critical to advance diabetes research. The Integrated Islet Distribution Program (IIDP), a major source for human islet distribution for over 15 years, conducted a study to evaluate the most ...
Barbara J. Olack   +13 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A nationwide annual characterization of 25 years of forest disturbance and recovery for Canada using Landsat time series

open access: yes, 2017
In the context of complex demands on forest resources and climate change, synoptic and spatially-explicit baseline data characterizing national trends in forest disturbance and subsequent return of vegetation (and eventual return to forest) are ...
Joanne C. White   +4 more
semanticscholar   +1 more source

Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study

open access: yesClinical Epidemiology, 2020
Robel Hussen Kabthymer,1 Getu Gizaw,2 Tefera Belachew2 1Human Nutrition Unit, School of Public Health, Dilla University, Dilla, Ethiopia; 2Department of Population and Family Health, College of Health Sciences, Jimma University, Jimma ...
Hussen Kabthymer R, Gizaw G, Belachew T
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Mental Health Staff Perspectives on Personal Recovery: A Narrative Study on Positive Professional Impact of Recovery-Oriented Care

open access: yes
ObjectivesMental health staff play an important role in facilitating personal recovery. We examined how mental health staff perceived personal recovery and the impact of their experience with supporting personal recovery.Research Design and MethodsForty ...
Kirkegaard Thomsen, Dorthe   +3 more
core   +1 more source

Recovery Time Considerations in Real-Time Systems Employing Software Fault Tolerance [PDF]

open access: yes, 2018
Safety-critical real-time systems like modern automobiles with advanced driving-assist features must employ redundancy for crucial software tasks to tolerate permanent crash faults.
Samii, Soheil   +2 more
core   +1 more source

Time to Recovery of Severely Ill COVID-19 Patients and its Predictors: A Retrospective Cohort Study in Tigray, Ethiopia

open access: yesJournal of Multidisciplinary Healthcare, 2022
Haftom Temesgen Abebe,1,2 Yibrah Berhe Zelelow,3 Afework Mulugeta Bezabih,4 Mengistu Mitiku Ashebir,5 Getachew Redae Tafere,6 Alem Desta Wuneh,5 Medhanie Gebresilassie Araya,7 Nguse Kahsay Kiros,8 Molla Kahssay Hiluf,9 Mohamedawel Mohamedniguss Ebrahim ...
Abebe HT   +12 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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