Results 91 to 100 of about 2,310,152 (342)
Understanding patient perspectives on management of their chronic pain: online survey protocol
Manasi Gaikwad,1,2 Simon Vanlint,1 G Lorimer Moseley,2,3 Murthy N Mittinty,4 Nigel Stocks1 1Discipline of General Practice, School of Medicine, University of Adelaide, Adelaide, SA, 2Sansom Institute for Health Research, University of South Australia ...
Gaikwad M +4 more
doaj
Optimal Time to Ship Human Islets Post Tissue Culture to Maximize Islet Recovery
Access to functional high-quality pancreatic human islets is critical to advance diabetes research. The Integrated Islet Distribution Program (IIDP), a major source for human islet distribution for over 15 years, conducted a study to evaluate the most ...
Barbara J. Olack +13 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
In the context of complex demands on forest resources and climate change, synoptic and spatially-explicit baseline data characterizing national trends in forest disturbance and subsequent return of vegetation (and eventual return to forest) are ...
Joanne C. White +4 more
semanticscholar +1 more source
Robel Hussen Kabthymer,1 Getu Gizaw,2 Tefera Belachew2 1Human Nutrition Unit, School of Public Health, Dilla University, Dilla, Ethiopia; 2Department of Population and Family Health, College of Health Sciences, Jimma University, Jimma ...
Hussen Kabthymer R, Gizaw G, Belachew T
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
ObjectivesMental health staff play an important role in facilitating personal recovery. We examined how mental health staff perceived personal recovery and the impact of their experience with supporting personal recovery.Research Design and MethodsForty ...
Kirkegaard Thomsen, Dorthe +3 more
core +1 more source
Recovery Time Considerations in Real-Time Systems Employing Software Fault Tolerance [PDF]
Safety-critical real-time systems like modern automobiles with advanced driving-assist features must employ redundancy for crucial software tasks to tolerate permanent crash faults.
Samii, Soheil +2 more
core +1 more source
Haftom Temesgen Abebe,1,2 Yibrah Berhe Zelelow,3 Afework Mulugeta Bezabih,4 Mengistu Mitiku Ashebir,5 Getachew Redae Tafere,6 Alem Desta Wuneh,5 Medhanie Gebresilassie Araya,7 Nguse Kahsay Kiros,8 Molla Kahssay Hiluf,9 Mohamedawel Mohamedniguss Ebrahim ...
Abebe HT +12 more
doaj
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source

