Results 101 to 110 of about 4,113,390 (286)

Time to recovery from severe community-acquired pneumonia and its predictors among 6 to 59 months of age children admitted to South Wollo zone public hospitals, North East Ethiopia: a prospective follow-up study

Pneumonia
Introduction Ethiopia is one of those countries with higher burden of community acquired pneumonia among its people, under five children are the members of society that are highly affected by pneumonia particularly Severe Community Acquired Pneumonia ...
Mekonnen Teferi, Elsabeth Addisu, Shambel Wodajo, Amare Muche, Abel Endawekie, Bezawit Adane, Tilahun Dessie, Natnael Kebede   +7 more
doaj   +1 more source

Clinical Features and Time to Recovery of Admitted COVID-19 Cases at Dilla University Referral Hospital Treatment Center, South Ethiopia

Infection and Drug Resistance, 2022
Gemechu Churiso,1 Kuma Diriba,1 Henok Girma,2 Soressa Tafere3 1Department of Medical Laboratory Sciences, Dilla University, Dilla, Ethiopia; 2Ohio State University, Global One Health Initiative, Dilla, Ethiopia; 3COVID-19 Treatment Center, Dilla ...
Churiso G, Diriba K, Girma H, Tafere S
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Effect of oliceridine versus morphine on the quality of early recovery after thoracoscopic surgery: a randomized, controlled clinical trial

BMC Anesthesiology
Background Thoracic surgery is frequently accompanied by severe pain. Although opioids remain the primary choice for effective analgesia in acute moderate-to-severe pain, their use is limited by adverse effects.
Xueqing Na, Ying Chen, Xin Liu, Jian Yang, Miao Tan, Yun Zhou, Man Shi, Jie Ouyang, Yongyu Si   +8 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Nominal Differences in Acute Symptom Presentation and Recovery Duration of Sport-Related Concussion Between Male and Female Collegiate Athletes in the PAC-12

Sports Medicine - Open
Background Sport-related concussion (SRC) is a heterogenous injury that often presents with varied symptoms and impairment. Recently, research has focused on identifying subtypes, or clinical profiles of concussion to be used in assessing and treating ...
Niki A. Konstantinides, Sean M. Murphy, Bridget M. Whelan, Kimberly G. Harmon, Sourav K. Poddar, Theresa D. Hernández, Rachel K. Rowe   +6 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Duration of recovery from severe acute malnutrition and associated factors in children aged 6–59 months: a retrospective cohort study

Scientific Reports
Malnutrition, particularly severe acute malnutrition (SAM) in children under five, is a global crisis affecting 25–35 million children, especially in Africa and Southeast Asia. In Ethiopia, 21% are underweight, 36% stunted, and 7% wasted.
Hikma Fedlu, Lata Fekadu, Amanuel Mengistu Merera, Kumara Asafa, Firew Tiruneh   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source