Results 81 to 90 of about 93,235,820 (285)
Clinical Epidemiology, 2020 Robel Hussen Kabthymer,1 Getu Gizaw,2 Tefera Belachew2 1Human Nutrition Unit, School of Public Health, Dilla University, Dilla, Ethiopia; 2Department of Population and Family Health, College of Health Sciences, Jimma University, Jimma ...
Hussen Kabthymer R, Gizaw G, Belachew T
doaj
Optimal Time to Ship Human Islets Post Tissue Culture to Maximize Islet Recovery
Cell Transplantation, 2020 Access to functional high-quality pancreatic human islets is critical to advance diabetes research. The Integrated Islet Distribution Program (IIDP), a major source for human islet distribution for over 15 years, conducted a study to evaluate the most ...
Barbara J. Olack +13 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Journal of Multidisciplinary Healthcare, 2022 Haftom Temesgen Abebe,1,2 Yibrah Berhe Zelelow,3 Afework Mulugeta Bezabih,4 Mengistu Mitiku Ashebir,5 Getachew Redae Tafere,6 Alem Desta Wuneh,5 Medhanie Gebresilassie Araya,7 Nguse Kahsay Kiros,8 Molla Kahssay Hiluf,9 Mohamedawel Mohamedniguss Ebrahim ...
Abebe HT +12 more
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Differences in five kilometer time trial performance during the recovery period after an ultramarathon race [PDF]
, 2013 Includes abstract.Includes bibliographical references.Athletes require an appropriate balance between training, competition stress and recovery to achieve maximal performance. Previous studies have shown that exercise induced muscle damage has a negative
Benney, Tamlyn
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source