Results 61 to 70 of about 2,310,152 (342)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Understanding the Relationship Between Key Clinical Variables of Childhood Malnutrition and Time-To-Recovery In Guatemala

open access: yes, 2023
Guatemala has the highest rates of malnutrition in Latin America, and with the onset of the COVID-19 pandemic, the number of Guatemalans experiencing food insecurity doubled.
Braxton, Morgan E   +1 more
core  

Service recovery following dysfunctional consumer participation [PDF]

open access: yes, 2012
This article introduces the notion of dysfunctional consumer participation. It advances a theoretical model of service recovery for contexts in which the smooth functioning of a service has been disrupted by consumers’ dysfunctional contributions ...
Maria G. Piacentini   +5 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Basic Psychological Need Satisfaction, Recovery State, and Recovery Timing [PDF]

open access: yesHuman Performance, 2018
This study aimed to provide insight into recovery from work-related load effects by examining (1) whether basic psychological need satisfaction (BPN satisfaction) during non-work days facilitates recovery; (2) whether the effect of BPN satisfaction is stronger in case of an unfavorable initial recovery state; and (3) whether the association between BPN
van Hooff, M.L.M.   +4 more
openaire   +4 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Recovery time of macroinvertebrate community from Cd pollution in Longjiang River, Guangxi, China

open access: yes, 2021
Estimating recovery times from pollution incident is an important issue of targeted biomonitoring programs. In the present study, the impact and recovery of macroinvertebrate communities from a cadmium wastewater discharge in the Longjiang River, Guangxi,
Wang, H   +4 more
core   +1 more source

Time-to-Recovery from Severe Pneumonia and Its Determinants Among Children Under-Five Admitted to University of Gondar Comprehensive Specialized Hospital in Ethiopia: A Retrospective Follow-Up Study; 2015–2020

open access: yesPediatric Health, Medicine and Therapeutics, 2021
Tigabnesh Assfaw,1 Chalachew Yenew,1 Kassahun Alemu,2 Wullo Sisay,2 Teshome Geletaw3 1Public Health, College of Medicine and Health Science, Debre Tabor University, Debre Tabor, Ethiopia; 2Public Health, College of Medicine and Health Science, University
Assfaw T   +4 more
doaj  

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