Results 81 to 90 of about 17,840,064 (257)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Description of boiling project burnout detector
Introduction: In order to effectively utilize the high heat flux available through the mechanism of nucleate boiling in forced convection heat transfer, it is of primary importance that the maximum flux or "burnout" conditions be known for the liquid ...
Reynolds John Mitchell, Raymond, M. W.
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Oregon T2 Center's Oregon roads newsletter summer 1998-
Information about serial cessation provided by Oregon Department of Transportation on May 25, 2022."A quarterly publication for local governments responsible for roads, bridges, and public transportation."Title from captionMode of access: Internet from ...
core
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Academic Spin-Off's Transfer Speed - Analyzing the Time from Leaving University to Venture [PDF]
For academic spin-offs I analyze the length of time between the founder's leaving of academia and the establishment of his firm. Technology transfer can take place even years after leaving the mother institution. A duration analysis reveals that a longer
Kathrin Müller
core
Influence of Precise Products on the Day-Boundary Discontinuities in GNSS Carrier Phase Time Transfer. [PDF]
Zhang X +6 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Heat transfer to impacting drops and post critical heat flux dispersed flow
Heat transfer to drops impacting on a hot surface is examined in context of dispersions of flowing, boiling fluids. The liquid contribution to heat transfer from a hot tube to a two-phase dispersion is formulated in terms of heat transfer contributions ...
Kendall, Gail E., Rohsenow, Warren M.
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

