Results 61 to 70 of about 1,621,990 (261)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Remote Sensing, 2019 The combination of transfer learning and remote sensing image processing technology can effectively improve the automation level of image information extraction from a remote sensing time series.
Xingli Qin +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Time dependent heat transfer of proliferation resistant plutonium
Nuclear Engineering and Technology, 2019 Increasing proliferation resistance of plutonium by way of increased 238Pu content is of interest to the nuclear nonproliferation and international safeguards community.
Cody Lloyd +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Time Traveling Regularization for Inverse Heat Transfer Problems
Energies, 2018 This work presents a technique called Time Traveling Regularization (TTR) applied to an optimization technique in order to solve ill-posed problems. This new methodology does not interfere in the minimization technique process.
Elisan dos Santos Magalhães +3 more
doaj +1 more source
Prediction for Chaotic Time Series-Based AE-CNN and Transfer Learning
Complexity, 2020 It has been a hot and challenging topic to predict the chaotic time series in the medium-to-long term. We combine autoencoders and convolutional neural networks (AE-CNN) to capture the intrinsic certainty of chaotic time series.
Baogui Xin, Wei Peng
doaj +1 more source
Psychology, 2013 The goal of the article is to definite that sleep with sufficient time and depth is a high quality sleep regardless of whether the sleep time changes or not. The author had conducted an experiment about sleep time. During the experiment, the author changed participants’ main sleep time four times. The result of the survey shows that participants take a
openaire +2 more sources