Results 71 to 80 of about 1,621,990 (261)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Performance Assessment of Undifferenced GPS/Galileo Precise Time Transfer with a Refined Clock Model
Remote SensingConventional Global Navigation Satellite System (GNSS) time transfer algorithms typically model receiver clock offsets as white noise for estimation, neglecting the physical characteristics of atomic clocks, which consequently limits the performance of ...
Wei Xu +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
SIMILARITY-BASED MULTI-SOURCE TRANSFER LEARNING APPROACH FOR TIME SERIES CLASSIFICATION
International Journal of Prognostics and Health Management, 2022 This study aims to develop an effective method of classification concerning time series signals for machine state prediction to advance predictive maintenance (PdM). Conventional machine learning (ML) algorithms are widely adopted in PdM, however, most
Ayantha Senanayaka +8 more
doaj +1 more source
Statistics for quantifying aging in time transfer system delays. [PDF]
Metrologia, 2023 Parker TE, Brown RC, Sherman JA.
europepmc +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Invariance times transfer properties
Probability, Uncertainty and Quantitative RiskInvariance times are stopping times $τ$ such that local martingales with respect to some reduced filtration and an equivalently changed probability measure, stopped before $τ$ , are local martingales with respect to the original model filtration and probability measure.
openaire +2 more sources
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Influence of Precise Products on the Day-Boundary Discontinuities in GNSS Carrier Phase Time Transfer. [PDF]
Sensors (Basel), 2021 Zhang X +6 more
europepmc +1 more source