Results 121 to 130 of about 2,772,692 (284)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Biological Time Travel: Tracking the Journey of Alloreactive T Cells Through Longitudinal Biobanking. [PDF]
Transplantation, 2023 Allocco J, Alegre ML.
europepmc +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Bodies in Space and Time Time Travel in Interstellar(Christopher Nolan, US/UK 2014)
Journal for Religion, Film and MediaThis article discusses the motif of time travel in the science-fiction film Interstellar (Christopher Nolan, US/UK 2014). Time travel is a common motif in modern science-fiction films and series.
Mündlein, Jochen
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Space, time, and time travel [PDF]
Newton supported the idea of absolute time, unlike Leibniz, for which time is only a relation between events and cannot be expressed independently, a statement in concordance with the relativity of space-time.
Sfetcu, Nicolae
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Beaming Bodies: A Neo-Lockean Account of Material Persistence
PhilosophiesConventional wisdom holds that human bodies do not and cannot persist through beaming: scanning and destruction of the body, followed by transmission of the scan information and replication of the body in another location.
Richard Mark Hanley
doaj +1 more source
Mental time travel ability influences the representation of events and emotional expressions: evidence from microblogs. [PDF]
BMC Psychol, 2023 Sun Z, Li Q, Luo F, Xu L.
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source