Results 141 to 150 of about 16,788,032 (264)

Time-Life Books, eds. The studio

, 1976
Life lib of photography236 p.; 25 ...
Time-life Int.
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Work, Rest, and Play: Exploring Trends in Time Allocation in Canada and the United States [PDF]

We control for demographic changes to document trends in the allocation of time using time diary data for Canada (1986 to 2005) and the United States (1985 to 2005).
McFarlane, Adian, Tedds, Lindsay
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Time Trends in Excess Mortality Among Individuals With Bipolar Disorder in Finland, 2000-2023: A Nationwide Register Study. [PDF]

Bipolar Disord
Rimmington J, Lumme S, Suokas K, Gutvilig M, Elovainio M, Hakulinen C.   +5 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Partially Virtual vs In-Person Care in Cardiovascular Conditions-Time Trends, Patient Characteristics, and Medication Management: Cohort Study. [PDF]

J Med Internet Res
Nielsen SK, Meddis A, Blanche PF, Hashiba M, Schou M, Kirk UB, Kayser L, Torp-Pedersen C, Nouhravesh N, Risom SS, Holt A, Lamberts MK.   +11 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Trends in commuter and leisure travel in The Netherlands 1991-2001 - Mode choice and travel time [PDF]

Data collected over recent years indicates that there has been an increase in the average distance of trips made, in the Netherlands (e.g. in 1985 the average trip made was 8.7 km, in 2000 the average trip length was 10.6 km (Harms, 2003)).
Christy Collins, Arianne De Blaeij
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Time trends in stroke incidence and modifiable risk factor prevalence in England (2018-2024): A record linkage population-based study. [PDF]

PLoS Med
Kamtchum-Tatuene J, Farrell J, Nolan J, Lessels S, Whiteley WN, Li L, CVD-COVID-UK/COVID-IMPACT Consortium.   +6 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source