Results 41 to 50 of about 16,788,032 (264)

Widening Educational Inequalities in Physical Health Due to the Obesity Trend?—A Mediation Analysis Using the German Socio-Economic Panel Study

International Journal of Public Health
Objectives:This study examined the contribution of obesity to the development of educational inequalities in physical health.Methods:We used data from the German Socio-Economic Panel for the period 2002–2020.
Stefanie Sperlich, Johannes Beller, Batoul Safieddine, Juliane Tetzlaff, Siegfried Geyer   +4 more
doaj   +1 more source

Who, where, when: Colorectal cancer disparities by race and ethnicity, subsite, and stage

Cancer Medicine, 2023
Background There are well‐established disparities in colorectal cancer (CRC) outcomes between White and Black patients; however, assessments of CRC disparities for other racial/ethnic groups are limited.
Kristin M. Primm, Andrea Joyce Malabay, Taylor Curry, Shine Chang   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Trends in socioeconomic inequalities in life expectancy and lifespan variation in Chile

Frontiers in Public Health
BackgroundSocioeconomic disparities in life expectancy are well-documented in various contexts, including Chile. However, there is a lack of research examining trends in life expectancy inequalities and lifespan variation over time. Addressing these gaps
Nicolas Silva-Illanes, Nicolas Silva-Illanes   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Modelling multi-state health transitions in China: a generalised linear model with time trends [PDF]

, 2019
Rapid population ageing in China has urged the need to understand health transitions of older Chinese to assist the development of social security programmes and financial products aimed at funding long-term care. In this paper, we develop a new flexible
Hanewald, K ; https://orcid.org/, Katja Hanewald, Li, H, Shao, AW, Han Li, Adam W. Shao   +5 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Effect of the economic crisis on the use of health and home care services among Spanish COPD patients

International Journal of COPD, 2018
Javier de Miguel-Diez,1 Ana Lopez-de-Andres,2 Valentin Herandez-Barrera,2 Isabel Jimenez-Trujillo,2 Luis Puente-Maestu,1 Alicia Cerezo-Lajas,1 Rodrigo Jimenez-Garcia2 1Respiratory Department, Hospital General Universitario Gregorio Marañón,
de Miguel-Diez J, Lopez-de-Andres A, Hernandez-Barrera V, Jimenez-Trujillo I, Puente-Maestu L, Cerezo-Lajas A, Jimenez-Garcia R   +6 more
doaj  

Increasing glucose concentrations and prevalence of diabetes mellitus in northern Sweden, 1990–2007

Global Health Action, 2010
Background: The prevalence of diabetes in the world is projected to rise from 2.8% in the year 2000 to 4.4% in 2030, an increase suggesting an ongoing global epidemic of diabetes.
Bernt Lindahl, Hans Stenlund, Margareta Norberg   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source