Results 91 to 100 of about 808,221 (264)
The Forecasting of Aluminum Prices: A True Challenge for Econometric Models
This paper explores the forecasting of aluminum prices using various predictive models dealing with variable uncertainty. A diverse set of economic and market indicators is considered as potential price predictors.
Krzysztof Drachal, Joanna Jędrzejewska
doaj +1 more source
Structural changes in the Czech, Slovak and euro area economies during the Great Recession
The goal of this paper is to identify and compare the most important changes in the structure of the Czech economy, as a small open economy with independent monetary policy, the Slovak economy, as a small open economy that entered monetary union, and the
Tvrz Stanislav, Vašíček Osvald
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We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Investigating Fiscal and Monetary Policy Coordination in Iran\'s Economy: TVP-Reaction Function
This study investigates whether monetary and fiscal policies are consistent in reaction to the demand pressure and inflationary conditions. To answer this question, the coordination between monetary and fiscal policies was examined for the period 1988:1 ...
Zhale Zarei, Maryam Hemmati
doaj
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
How to go viral: A COVID-19 model with endogenously time-varying parameters. [PDF]
Ho P, Lubik TA, Matthes C.
europepmc +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
An Estimation Algorithm for General Linear Single Particle Tracking Models with Time-Varying Parameters. [PDF]
Godoy BI, Vickers NA, Andersson SB.
europepmc +1 more source

