Results 31 to 40 of about 400,980 (279)
Evaluation of the foetal time to death in mice after application of direct and indirect euthanasia methods [PDF]
Laboratory Animals, 2015 Directive 2010/63/EU on the protection of animals used for scientific purposes requires that the killing of mammal foetuses during the last third of their gestational period should be accomplished through effective and humane methods.
C, Muñoz-Mediavilla +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
End-of-life hospitality? A preamble for supply-side notions of suicide tourism [PDF]
Journal of Tourism, Heritage & Services MarketingPurpose: Suicide tourism has existed for several decades in countries such as Switzerland, allowing inbound tourists to seek death with dignity. The growth of suicide tourism has not gone unnoticed, with an emerging body of work unpacking this phenomenon,
Aaron Tham , Hayley Stainton
doaj +1 more source
The future of euthanasia politics in the Australian state parliaments [PDF]
, 2014 There has been significant activity on voluntary euthanasia, with bills seeking to reform the law on the practice introduced in all of the Australian state parliaments except Queensland.
Alison Plumb
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
A time to be born and a time to die: reflections on euthanasia
Journal of Psychosomatic Obstetrics & Gynecology, 2002 Euthanasia is, and probably will remain a controversial issue. Although many doctors will agree that under certain circumstances a demand for euthanasia should be granted (and in fact often is granted when the occasion arises), the subject generally gives rise to very emotional debates.
openaire +3 more sources
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Ожирение и метаболизм, 2020 BACKGROUND: Metabolic syndrome (MS) causes the risk of serious diseases development e.g. type 2 diabetes mellitus and cardiovascular disasters. Timely and adequate correction of MS can reduce the risk of heart disease and diabetes AIM: To investigate the
Cyril O. Tarimov +8 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
A case of orbital extra-adrenal paraganglioma in a quarter horse
Brazilian Journal of Veterinary Pathology, 2019 Paragangliomas are tumors originating from paraganglia cells which represent a considerable constituent of the dispersed neuroendocrine system. Rarely these tumors are found within the orbital region. This report documents a case of primary extra-adrenal
Letizia Tomassini +5 more
doaj +1 more source