Results 41 to 50 of about 400,980 (279)

Abortion, reproductive technology, and euthanasia:: Post-concolliar responses from within the Roman Catholic Church in England and Wales 1965-2000 [PDF]

, 2003
This thesis is the product of original research into the responses offered by the Roman Catholic Church in England and Wales to the subjects of abortion, reproductive technology, and euthanasia, during the years 1965 to 2000.
Wilson, John
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Influences on the Decision to Euthanize a Compromised Pig

Animals
The decision to euthanize a compromised pig can be challenging for pig farmers and veterinarians. To understand more about the challenges in Germany, a cross-sectional online survey was conducted.
Julia Stoffregen, Tristan Winkelmann, Bettina Schneider, Michel Fehrmann, Kathrin Gerdes, Moana Miller, Jennifer Reinmold, Isabel Hennig-Pauka, Nicole Kemper, Christin Kleinsorgen, Karl-Heinz Tölle, Lothar Kreienbrock, Michael Wendt, Elisabeth grosse Beilage   +13 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Electrocution as an alternative euthanasia method to blunt force trauma to the head followed by exsanguination for non-viable piglets

Acta Veterinaria Scandinavica, 2020
Background On farms, the currently approved and most widely practised method of euthanising non-viable piglets is blunt force trauma to the head followed by exsanguination.
Johannes Husheer, Matthias Luepke, Peter Dziallas, Karl-Heinz Waldmann, Alexandra von Altrock   +4 more
doaj   +1 more source

Computed Tomography‐ and Photoacoustic Imaging‐Active Bioresorbable Electrospun Bismuth Nanoparticle‐Infused Small‐Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena, Joy Vanessa D. Perez, Marvin R. Bernardino, Dominic Karl M. Bolinas, Kitz Paul D. Marco, Kim Claudette J. Fernandez, Archana Mishra, Erin Marie D. San Valentin, Jossana A. Damasco, Gino Martin Canlas, Natalie Fowlkes, Richard R. Bouchard, Steven Y. Huang, Marites P. Melancon   +13 more
wiley   +1 more source

Aspects and dilemmas of euthanasia in modern times

Scripta Medica
Euthanasia is a very complex medical and moral issue. The name has taken throughout history quite different meanings especially in recent decades. There have been many controversial debates and ethical questions raised in modern society. The aim of the paper was to introduce in more detail the issue of euthanasia in the modern world and to review the ...
Alen Greš, Dijana Staver, Ljubomir Radovančević   +2 more
openaire   +2 more sources

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Clinical, laboratory and ultrasonographic findings in 87 cows with type-4 abomasal ulcer

BMC Veterinary Research, 2019
Background This study evaluated the clinical, laboratory, ultrasonographic and pathological findings in 87 cows aged 2 to 10 years (4.5 ± 1.5 years) with type-4 abomasal ulcer.
Ueli Braun, Christina Reif, Karl Nuss, Monika Hilbe, Christian Gerspach   +4 more
doaj   +1 more source