Results 81 to 90 of about 424,131 (275)

Intensive Care Unit Nurses? Opinions About Euthanasia

open access: yes, 2007
This study was conducted to gain opinions about euthanasia from nurses who work in intensive care units. The research was planned as a descriptive study and conducted with 186 nurses who worked in intensive care units in a university hospital, a public ...
Kumas, Gülsah   +2 more
core   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

open access: yesAdvanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen   +10 more
wiley   +1 more source

Ontario dairy veterinarians' perspectives on down cow care, producer decision making, and implementation of recommended practices: A qualitative interview study

open access: yesJournal of Dairy Science
: The objective of this study was to examine Ontario dairy veterinarians' perspectives when working with producers on managing and caring for down dairy cows, focusing on protocols, current practices, implementation of best practices, and barriers.
John E. Brindle   +2 more
doaj   +1 more source

Euthanasia and the duty to die: a moral advocacy of the responsibility to end life at the right time

open access: yes, 2021
The general aim of this project is to investigate thoroughly the moral issues related to death and dying in medical contexts, focusing on those cases where patients seek help to die on their own terms. The focus of the debate in society at large tends to focus on the question of whether it is morally permissible for a patient to ask for help to die ...
openaire   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Euthanasia and Related Practices Worldwide

open access: yes, 1998
The present paper examines the occurrence of matters relating to the ending of life, including active euthanasia, which is, technically speaking, illegal worldwide.
Kelleher, Michael J.   +4 more
core   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

open access: yesAdvanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens   +11 more
wiley   +1 more source

Voluntary Active Euthanasia

open access: yes, 1992
I have cited both good and bad consequences that have been thought likely from a policy change permitting voluntary active euthanasia, and have tried to evaluate their likelihood and relative importance.
Brock, Dan W.
core   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

open access: yesAdvanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li   +12 more
wiley   +1 more source

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