Results 91 to 100 of about 1,407,102 (317)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Endogenous Timing in a Mixed Duopoly: The Managerial Delegation Case [PDF]
We introduce managerial delegation into Pal's (1998) model and examine the impact of the introduction of managerial delegation on endogenous timing in a mixed duopolistic model for differentiated goods.
Tomohiro Inoue, Yasuhiko Nakamura
core
Modeling circadian and sleep-homeostatic effects on short-term interval timing [PDF]
, 2015 Short-term interval timing i.e., perception and action relating to durations in the seconds range, has been suggested to display time-of-day as well as wake dependent fluctuations due to circadian and sleep-homeostatic changes to the rate at which an ...
Jakub eSpäti +23 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Timing of debt issues: Evidence from a panel of Tunisian and French firms [PDF]
Recent literature argues that market timing becomes the factor that shapes financing policies. However, empirical studies on debt market timing still less numerous than those on equity market timing.
Khemaies Bougatef, Jameleddine Chichti
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Risk Preferences and the Timing of Marriage and Childbearing [PDF]
The existing literature on marriage and fertility decisions pays little attention to the roles played by risk preferences and uncertainty. However, given uncertainty regarding the arrival of suitable marriage partners, the ability to contracept, and the ...
Lucie Schmidt
core +2 more sources
Interval timing, dopamine, and motivation
, 2015 The dopamine clock hypothesis suggests that the dopamine level determines the speed of the hypothetical internal clock. However, dopaminergic function has also been implicated for motivation and thus the effect of dopaminergic manipulations on timing ...
Balcı, Fuat
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A Hardware Design Language for Efficient Control of Timing Channels [PDF]
, 2014 Content file updated by author on 15 January 2015.Timing channels pose a real security risk, but methods are lacking for building systems without timing leaks.
Zhang, Danfeng +8 more
core