Results 81 to 90 of about 1,663,153 (257)

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Detection and characterisation of binary asteroid candidates through stellar occultations

Astronomy & Astrophysics
Context. Binary asteroids provide key access to fundamental parameters of Solar System remnants and planetary formations. However, the current knowledge of binary asteroids remains strongly biased by observational limitations, and main belt binary ...
Lallemand R., Desmars J., Sicardy B., Liu Z., Tanga P., Liberato L., Carry B., Leroy A., Kilic Y., Assafin M., Siakas A., Abe L., Mary D., Casarramona F., Smith D., Antuszewicz D., Dauvergne J.-L., Langin G., Henarejos P., Phan P.-L., Braga-Ribas F., Castro A., Pal A., Sódor Á., Cano Ruiz A., Pratt A., Noschese A., Manna A., Eberle A., Schweizer A., Wendelborn A., Marciniak A., Ziółkowski B., Begiçarslan B., Kattentidt B., Tezcan C. T., Weber C., Schnabel C., Domingues C. A., Ziolek C., Sartini C., Schäfer C. M., McPartlin C., Kiss Cs., Blazewicz D., Deneuchatel D., Herald D., Dunham D. W., Sailing D., Fonseca Morato E., Fernandez-Garcia E., Smith E., Gradovski E., Donate Lucas E., García Navarro E., Kaan Ülgen E., Garcia F., Genc F., Margoti G., Arraras G., Schmidt G., Privett G., Krannich G., Lyzenga G., de Groot H., Pérez-Garcia I., Kelkitli I. Z., Mánek J., Flores-Martín J., Prat J., Bardecker J., Siegert J., Dunham J., Moore J., Reyes J. A., Maestre J. L., Ortiz J. L., Perła J., Spagnotto J., Getrost K., Bath K.-L., Okasaki K., Bender K., OConnell M., Skrutskie M., Jennings M., Margoti M., Içen M., Acar M., Fidêncio Neto M., Altan M., Rottenborn M., Turchenko M., Alava Amat M. A., Kretlow M., Tekkesinoglu M., Takács N., Castro-Morales N., Morales N., Erece O., Canales Moreno O., Santos Sanz P., Fini P., Maley P. D., Teckenburg P., Walker P., Martorell P., Gilge P., Zeleny P., Stuart P., Ashimbekova A., Denyer P., Sfair R., Nolthenius R., Piety R., Liu R., Jones R., Szakáts R., Gonçalves R., Pastor S., Chairetas S., Kalkan S., Özel S., Ötken S., Aliş S., Tsavdaridis S., Meister S., Sposetti S., Conard S., Tirak S., Fisek S., Swift T., Haymes T., Janík T., Nikitin V., Hanna W., Dahoumane R., Ogloza W., Stewart W., Beisker W., Liu Y., Avcioglu Y., Quinet S., Counilh J.-F., Irzyk M., Marlot C., Keijzer A., Pinard Y., Salomon T., Mollier T., Valat S., Kindt S., Souchu J., Vasseur S., Dequinze R., Couvée P., Lemoine P., Barroy P., Mercier P.-J., André P., Le Guen P., Schreurs O., Boutet M., Giraud M., Lecossois M., Serrau M., Conjat M., Herrier L., Rousselot L., Delpau J., Bourgeois J., Dalouzy J.-C., Gout J.-F., Pittet J.-F., Coliac J.-F., Dumont J.-L., Nombret J.-P., Masini J.-P., Arnould J.-P., Marquette J.-B., Arlic G., Denjean F., Cavaillé F., Barbotin E., Bourdens D., Walliang D., Auvray I., Latgé C., Lavault C., Stachowicz A., Jacquet E., Rizand C., Raffard J., Saillenfest M., Hussein K., Montargès M., Robichon N., Renner S., Lapeyrére V., Thuillot W., Vachier F., Hestroffer D., Vienne A., Vaubaillon J., Bourdens C., Boninsegna R., Lin M.-C., Chen Y.-L., Tsai S. H., Lee C.-E., Lee Y.-N., Lin Z.-Y., Lin H.-C., Wang C.-H., Shen A. T. L., Chuang T.-H., Chang C.-C., Watanabe Ha., Ida M., Togashi H., Asai A., Nemoto T., Hosoi K., Watanabe Hi., Isobe K., Yoshihara H., Horikawa T., Kitazaki K., Takimoto M., Yamamura H., Yamashita M., Yoshida F., Gourdon F.   +232 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Self-Confidence and Timing of Entry [PDF]

This paper analyzes the impact of overconfidence on the timing of entry in markets, profits, and welfare. To do that the paper uses an endogenous timing model where (i) players have private information about costs and (ii) one player is overconfident and
Tiago Pires, Luís Santos-Pinto
core  

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

A Note on Endogenous Timing with Strategic Delegation: Unilateral Externality Case [PDF]

We investigated the endogenous choice of roles by managerial firms in the presence of unilateral externality. The choice over timing can be taken either by managers or by owners.
Kangsik Choi, Yuanzhu Lu
core  

Modeling circadian and sleep-homeostatic effects on short-term interval timing [PDF]

, 2015
Short-term interval timing i.e., perception and action relating to durations in the seconds range, has been suggested to display time-of-day as well as wake dependent fluctuations due to circadian and sleep-homeostatic changes to the rate at which an ...
Jakub eSpäti, Meyer, Andrea Hans, Moriguchi, Yoshiya, Aritake, Sayaka, Hida, Akiko, Sayaka Aritake, Mishima, Kazuo, Yoshiya eMoriguchi, Späti, Jakub, Kitamura, Shingo, Yoshiya Moriguchi, Shigekazu eHiguchi, Jakub Späti, Kazuo Mishima, Shingo eKitamura, Akiko eHida, Kazuo eMishima, Andrea H. Meyer, Sayaka eAritake, Higuchi, Shigekazu, Shingo Kitamura, Shigekazu Higuchi, Andrea Hans Meyer, Akiko Hida, Meyer AH, Späti J, Mishima K, Hida A, Higuchi S, Kitamura S, Moriguchi Y, Aritake S   +31 more
core   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Guanine is an inhibitor of c-jun terminal kinases

Scientific Reports
The toxicity of purine bases adenine and guanine is mostly recognized when associated with inborn errors of purine metabolism such as Lesch-Nyhan syndrome, and metabolic diseases with a lifestyle component including gout.
Jessica Treeby, Sherihan El-Sayed, Samuel Morgan, Sophie Maddock, George Taylor, Stacey Warwood, Julian Selley, David Knight, Benjamin Saer, Richard A. Bryce, Jean-Michel Fustin   +10 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source