Results 61 to 70 of about 3,301,881 (350)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Beyond Lux: methods for species and photoreceptor-specific quantification of ambient light for mammals

open access: yesBMC Biology
Background Light is a key environmental regulator of physiology and behaviour. Mistimed or insufficient light disrupts circadian rhythms and is associated with impaired health and well-being across mammals.
Richard J. McDowell   +8 more
doaj   +1 more source

Inherent Trade-Offs Between the Conflicting Aspects of Designing the Compact Global Navigation Satellite System (GNSS) Anti-Interference Array

open access: yesRemote Sensing
The Global Navigation Satellite System (GNSS) has emerged as a critical spatiotemporal infrastructure for ensuring the integrity of remote sensing data links. However, traditional GNSS antenna arrays, typically configured with the antenna spacing of half
Xiangjun Li   +5 more
doaj   +1 more source

Generative pulsar timing analysis

open access: yes, 2015
A new Bayesian method for the analysis of folded pulsar timing data is presented that allows for the simultaneous evaluation of evolution in the pulse profile in either frequency or time, along with the timing model and additional stochastic processes ...
Alexander, P., Hobson, M. P., Lentati, L
core   +1 more source

Cell-cycle regulated transcription associates with DNA replication timing in yeast and human [PDF]

open access: yes, 2013
Eukaryotic DNA replication follows a specific temporal program, with some genomic regions consistently replicating earlier than others, yet what determines this program is largely unknown.
Fraser, Hunter B.
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

The Sensitivity of the Parkes Pulsar Timing Array to Individual Sources of Gravitational Waves [PDF]

open access: yes, 2010
We present the sensitivity of the Parkes Pulsar Timing Array to gravitational waves emitted by individual super-massive black-hole binary systems in the early phases of coalescing at the cores of merged galaxies. Our analysis includes a detailed study of
A. W. Hotan   +54 more
core   +3 more sources

A survey of GNSS receiver autonomous integrity monitoring: Research status and opportunities

open access: yesFrontiers in Physics
Integrity monitoring is crucial in applications closely related to the safety of human life and property, such as aviation, maritime navigation, autonomous driving, and rail transportation.
Zhen Huang   +10 more
doaj   +1 more source

Time to treatment initiation and outcomes in high-grade glioma patients in rehabilitation: a retrospective cohort study

open access: yesCNS Oncology, 2020
Aims: To investigate wait time (WT) for chemoradiation and survival in post-op high-grade glioma (HGG) patients admitted to inpatient rehabilitation compared with those discharged home.
Kwanza T Warren   +8 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

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