Results 141 to 150 of about 1,663,153 (257)

Discussing Future Treatment and Care in the ICU: Perspectives From Patients. [PDF]

Acta Anaesthesiol Scand
Smith MA, Zwisler AD, Nissen A, Michelsen J, Olsen HT, Wichmann S, Hansen PM, Walther LH, Le Greves S, Westergaard B, Jensen HI, Nystrup KB.   +11 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Tooth Extraction Timing After Head and Neck Radiotherapy: A Critical Reappraisal of Osteoradionecrosis Risk and Biological Vulnerability. [PDF]

Methods Protoc
Topkan E, Somay E, Bascil S, Selek U.
europepmc   +1 more source

Implications of within-period timing in models of speculative attack [PDF]

Speculative attacks are often modeled as decreases in money demand before currency crises. I discuss how, in models with microfoundations, within-period timing affects whether attacks arise in equilibrium.
Antonio Doblas-Madrid
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Association Between Surgical Timing and In-Hospital Mortality in Infective Endocarditis: A Retrospective Single-Centre Study. [PDF]

Antibiotics (Basel)
Radu AM, Talpoși IF, Țoțoiu RE, Berbecaru RO, Dobrin A, Melinte V, Văcăroiu CM, Holban T, Popa MC, Călinoiu A, Popa OA, Iancu ME, Tomescu L, Săndulescu O, Gheorghiță V.   +14 more
europepmc   +1 more source

Endogenizing leadership in tax competition: a timing game perspective [PDF]

In this paper we extend the standard approach of horizontal tax competition by endogenizing the timing of decisions made by the competing jurisdictions.
Rota Graziosi, G., Kempf, H.
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Endogenous Timing in a Mixed Duopoly and Private Duopoly - ‘Capacity- then-Quantity’ Game [PDF]

We consider a game of endogenous timing of sequential choice of capacity and quantity with observable delay in a mixed duopoly and a private duopoly under two possible time structures.
Yuanzhu Lu, Sougata Poddar
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source