Results 161 to 170 of about 1,407,102 (317)

Timing of international market entry of UK and German high-tech start-ups [PDF]

We examine the impact of technological product advantages, prior international experience of the management, firm size and age, country differences, and sunk costs as determinants of the timing of international market entry.
Fier, Andreas, Murray, Gordon, Licht, Georg, Bürgel, Oliver   +3 more
core  

Processing speed deficits: A missing link in understanding individual variation in children's interval timing skills? [PDF]

Dev Psychol
Parr MNDN, Noonan M, Noferesti I, Wang J, Stoffel J, O'Neal EE, Kearney JK, Plumert JM.   +7 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Editorial: Disambiguating pubertal status from pubertal timing during adolescence: A renewed call for improved construct definition and measurement. [PDF]

J Child Psychol Psychiatry
Klump KL, Di Dio AM, Culbert KM.
europepmc   +1 more source

Time Past, Time Present, Time Future [PDF]

The Behavior Analyst, 1989
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Determine the optimal ignition timing function based on combustion duration, load and fuel blending ratio of an engine powered with diesel-methanol blends. [PDF]

PLoS One
Hong TD, Phan DQ, Do SH, Duong LH, Pham MQ, Nghiem QTP.   +5 more
europepmc   +1 more source

It Is Time [PDF]

Annals of Surgical Oncology, 2019
Kiran K, Turaga, T Clark, Gamblin, Robert, Edwards, H Richard, Alexander, David, Bartlett   +4 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Listeners near-optimally integrate acoustic and semantic cues in spoken word recognition: Evidence from experiments manipulating cue order and reliability. [PDF]

Atten Percept Psychophys
Westwig A, Kim Y, Bushong W.
europepmc   +1 more source