New step-by-step retrofitting model for delivering optimum timing
Iná Maia, Lukas Kranzl, Andreas Müller
openalex +1 more source
Embedded timing and alert device triggered by total dissolved solids (TDS) for monitoring disinfection duration in acidic electrolyzed oxidizing water. [PDF]
Zheng W, Xu H, Mao Y, He F, Gui P.
europepmc +1 more source
Time for Time: There’s No Time, We Have Time
A short film online showing an encounter between an Indonesian bulldozer operator and two natives of an indigenous tribe on the island of Halmahera initiates a reflection on the clash and collision of the many times in which we live and reasons for the increasing importance of modern temporal consciousness.
openaire +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Timing of dexamethasone initiation during controlled ovarian stimulation and live birth after IVF/ICSI: a retrospective cohort study. [PDF]
Zhang L +5 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Consistently longer silent gaps in autistic speaker pairs across three conversational contexts. [PDF]
Wehrle S, Spaniol M, Vogeley K, Grice M.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Timing of meteoric-water incursion controls the scale of tin mineralization
Liu, Peng
openalex +1 more source

