Results 101 to 110 of about 13,975,826 (243)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Statistical Sequential Path Delay Variation Model with Lognormal Distribution for Low-Voltage Circuit

Applied Sciences
To solve the timing uncertainty in low-voltage circuits, this paper proposes an analytical sequential path delay model based on the lognormal distribution.
Runkan Liu, Dongmin Zhao, Jingjing Guo
doaj   +1 more source

From hell to heaven? Evidence of migration trajectories from an Italian refugee centre

Demographic Research, 2018
Background: In recent years, large numbers of migrants have attempted to reach Europe by crossing the Mediterranean Sea. Italy plays a central role as a receiving country, particularly because of its relative proximity to the coast of North Africa ...
Manuela Stranges, François-Charles Wolff   +1 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Timing of debt issues: Evidence from a panel of Tunisian and French firms [PDF]

Recent literature argues that market timing becomes the factor that shapes financing policies. However, empirical studies on debt market timing still less numerous than those on equity market timing.
Khemaies Bougatef, Jameleddine Chichti
core  

The timing of elective caesarean delivery between 2000 and 2009 in England. [PDF]

, 2011
BACKGROUND: In 2004, the National Institute for Clinical Excellence (NICE) recommended that an elective caesarean section for an uncomplicated pregnancy should not be carried out before 39 completed weeks due to increased risk of respiratory morbidity in
Onwere, Chidimma, Chidimma Onwere, David A Cromwell, Gurol-Urganci Ipek, Cromwell, David A., Gurol-Urganci, Ipek, Mahmood, Tahir A, van der Meulen, Jan H, Edozien, Leroy C., Tahir A Mahmood, Onwere Chidimma, Leroy C Edozien, Edozien Leroy C, Jan H van der Meulen, Cromwell, David A, Cromwell David A, Mahmood, Tahir A., Edozien, Leroy C, Mahmood Tahir A, van der Meulen, Jan H., van der Meulen Jan H, Ipek Gurol-Urganci   +21 more
core   +2 more sources

Market timing: A decomposition of mutual fund returns [PDF]

We decompose the conditional expected mutual fund return in five parts. Two parts, selectivityand expert market timing, can be attributed to manager skill, and three to variation in marketexposure that can be achieved by private investors as well.
Swinkels, L.A.P., Sluis, P.J. van der, Verbeek, M.J.C.M.   +2 more
core   +2 more sources

Long-term monitoring of sand fly populations: temporal responses to land-use change and climatic variability

Parasites & Vectors
Background Phlebotomine sand flies are the sole vector of leishmaniasis and other sand fly–borne diseases, and their populations are shaped by climate and human-driven environmental change.
Yoni Waitz, Shlomit Paz, Shirly Elbaz, Debora Diaz, Ira Ben-Avi, Liora Studentsky, Eran Hacklai, Shai Reicher, Ron Drori, Maia Davidovich-Cohen, Laor Orshan, Oscar David Kirstein   +11 more
doaj   +1 more source

The role of smoking on mortality compression: An analysis of Finnish occupational social classes, 1971-2010

Demographic Research, 2015
Background: Adult lifespan variation has been stagnant since the 1960s in most developed countries, despite increases in longevity. However, national averages mask large socioeconomic differences.
Alyson van Raalte, Mikko Myrskylä, Pekka Martikainen   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source