Results 91 to 100 of about 30,734 (250)

Effects of analysis of posterior subtenon injection of triamcinolone: a case series [PDF]

, 2006
PURPOSE: To evaluate the effects of posterior subtenon injection of triamcinolone acetonide in patients with intraocular inflammation. METHODS: Case series enrolling 24 patients (26 eyes) submitted to posterior subtenon injection of triamcinolone ...
Moraes, Remo Turchetti, Muccioli, Cristina, Zajdenweber, Moysés Eduardo   +2 more
core   +3 more sources

Protothecosis in Dogs: A Narrative Review

Journal of Veterinary Internal Medicine, Volume 39, Issue 2, March/April 2025.
ABSTRACT Protothecosis is a rare and unusual disease that affects both humans and animals, including dogs. The causative agents are unicellular, achlorophyllous, “yeast‐like” microalgae of the genus Prototheca (Trebouxiophyceae, Chlorophyta). Although usually saprophytic, Prototheca may, under conditions of immunologic compromise, become pathogenic and
Tomasz Jagielski, Angelika Proskurnicka, Mateusz Iskra, Sylwia Wronka, Zofia Bakuła, Patrizia Danesi, Marconi Rodrigues de Farias, Fábio Vinícius Ramos Portilho, Márcio Garcia Ribeiro, Uwe Rösler, Rui Kano, Richard Malik   +11 more
wiley   +1 more source

Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]

, 2018
Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
core   +1 more source

Colloid‐Forming Prodrug‐Hydrogel Composite Prolongs Lower Intraocular Pressure in Rodent Eyes after Subconjunctival Injection

Advanced Materials, Volume 37, Issue 8, February 25, 2025.
Colloidal drug aggregates (CDAs) are repurposed as a platform for long‐acting ocular drug delivery. Timolol palmitate CDAs are stabilized within an in situ gelling hydrogel and injected subconjunctivally, reducing intraocular pressure (IOP) for 49 d with lower systemic exposure compared to conventional eye drops.
Mickael Dang, Kai V. Slaughter, Hong Cui, Christopher Jiang, Lisa Zhou, David J. Matthew, Jeremy M. Sivak, Molly S. Shoichet   +7 more
wiley   +1 more source

A novel stability indicating RP-HPLC method of related substances for dorzolamide hydrochloride and timolol maleate in glaucoma treatment ophthalmic formulation

Discover Chemistry
A sensitive and simultaneous RP-HPLC strategy has been developed for analysing timolol maleate and dorzolamide hydrochloride along with their related substances.
Harmeet Kaur Kohli, Satish K. Ghumare, Vijay A. Bagul   +2 more
doaj   +1 more source

Long-term cost and efficacy analysis of latanoprost versus timolol in glaucoma patients in Germany

International Journal of Ophthalmology, 2013
AIM: To evaluate 5-year effectiveness and cost between latanoprost or timolol monotherapy in a pilot trial. METHODS: A retrospective, multi-center trial performed at 6 sites in Germany of patients who had a diagnosis of primary open-angle or ...
Jeanette A. Stewart, Lindsay A. Nelson, Michael S. Kristoffersen, Sonja Schölzel, Dietmar Schnober, Ulrich Thelen, William C. Stewart   +6 more
doaj   +1 more source

Fish Fin‐Derived Non‐Invasive Flexible Bioinspired Contact Lens for Continuous Ophthalmic Drug Delivery

Advanced Science, Volume 12, Issue 6, February 10, 2025.
Inspired by the structure and reciprocating motion of fish dorsal fins, a drug‐eluting contact lens based on deformable microstructures for non‐invasive drug delivery is developed. The drug release rate can be adaptively adjusted to intraocular pressure changes and proactively regulated by cyclic ocular loads, enabling it to respond to elevated ...
Xu Li, Hui Li, Zihao Wang, Xianda Wang, Jinlong Zhang, Fengjiao Bin, Wei Chen, Hongyang Li, Dongmei Huo, Dengbao Xiao   +9 more
wiley   +1 more source

FORMULATION AND CHARACTERIZATION OF TIMOLOL MALEATE-LOADED NANOPARTICLES GEL BY IONIC GELATION METHOD USING CHITOSAN AND SODIUM ALGINATE

International Journal of Applied Pharmaceutics, 2019
Objective: The objectives of this study were to formulate and characterize nanoparticles gel of timolol maleate (TM) by ionic gelation method using chitosan (CS) and sodium alginate (SA).
Risa Ahdyani, Laras Novitasari, R. Martien   +2 more
semanticscholar   +1 more source

Assessment of ocular hypotensive effect and safety 12 months after changing from an unfixed combination to a latanoprost 0.005% + timolol maleate 0.5% fixed combination

Clinical Ophthalmology, 2012
Kenji Inoue1, Ryoko Okayama1, Risako Higa1, Masato Wakakura1, Goji Tomita21Inouye Eye Hospital, 4-3 Kanda-Surugadai, Chiyoda-ku, 2Second Department of Ophthalmology, Toho University School of Medicine, Meguro-ku, Tokyo, JapanBackground: Latanoprost 0.005%
Inoue K, Okayama R, Higa R, Wakakura M, Tomita G   +4 more
doaj  

Quantification method for timolol from in vivo samples for the development of a new glaucoma drug depot

Current Directions in Biomedical Engineering, 2018
Glaucoma is the second most common cause of blindness. An increased intraocular pressure is the only treatable symptom of glaucoma. Because patients often exhibit a poor therapy adherence, a drug depot consisting of ELA-NCO and hyaluronic acid with ...
Eickner Thomas, Kopp Franziska, Brietzke Andreas, Kischkel Sabine, Oschatz Stefan, Schmitz Klaus-Peter, Guthoff Rudolf, Grabow Niels   +7 more
doaj   +1 more source