Results 81 to 90 of about 30,734 (250)

Effect of Topical Timolol on Healing of Immature Breast Scars After Mammoplasty: A Randomized Controlled Trial With Blinded Assessors and Patients

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Introduction Wound healing is a complex process encompassing four main stages: hemostasis, inflammation, cell proliferation, maturation, and differentiation. Timolol (TM) may influence these stages, particularly re‐epithelialization. This study aims to evaluate the 1‐month effects of timolol on acute surgical wounds in post‐mammoplasty ...
Nahid Nafissi   +9 more
wiley   +1 more source

Long-term 24-hour intraocular pressure control with travoprost monotherapy in patients with primary open-angle glaucoma [PDF]

open access: yes, 2014
The aim of the study was to evaluate the long-term 24-hour intraocular pressure (IOP) efficacy of travoprost monotherapy in primary open-angle glaucoma ...
Biagioli, Elena   +6 more
core   +1 more source

Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5% [PDF]

open access: yesEye, 2004
The diurnal efficacy and safety of the fixed combinations of latanoprost/timolol given once daily vs dorzolamide/timolol given twice daily in primary open-angle glaucoma or ocular hypertensive patients.A double-masked, two-centre, crossover comparison.In 33 patients, the mean diurnal IOP (0800-2000, measured every 2 h) for latanoprost/timolol fixed ...
A G P, Konstas   +5 more
openaire   +2 more sources

β‐Adrenergic Blockers Increase cAMP and Stimulate Insulin Secretion Through a PKA/RYR2/TRPM5 Pathway in Pancreatic β‐Cells In Vitro

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 2, April 2025.
At high concentrations (> 10 μM), the β‐adrenergic blocker propranolol paradoxically increased intracellular cAMP levels in pancreatic β‐cells. This led to PKA‐induced RYR2 phosphorylation and extracellular Ca2+ influx, leading to CICR from the ER. CICR activated TRPM5, which augmented β‐cell electrical activity, extracellular Ca2+ influx, and insulin ...
Naoya Murao   +6 more
wiley   +1 more source

Nanochanneled Device and Related Methods [PDF]

open access: yes, 2013
A capsule configured for in vivo refilling of a therapeutic agent.
Ferrari, Mauro   +4 more
core   +2 more sources

Visible‐Light Photo‐Iniferter Polymerization of Molecularly Imprinted Polymers for Direct Integration with Nanotransducers

open access: yesSmall Methods, Volume 9, Issue 4, April 22, 2025.
This study overcomes the challenges of integrating MIPs with nanostructured transducers for chemical sensing. It demonstrates precise MIP deposition on nanoporous silica (PSiO2) via controlled radical photopolymerization, achieving uniform thin films.
Tiziano Di Giulio   +8 more
wiley   +1 more source

Ocular hypotensive effect and safety of travoprost 0.004%/timolol maleate 0.5% fixed combination after change of treatment regimen from ß-blockers and prostaglandin analogs

open access: yesClinical Ophthalmology, 2012
Kenji Inoue1, Akira Setogawa1, Risako Higa1, Ryo Moriyama1, Masato Wakakura1, Goji Tomita21Inouye Eye Hospital, Chiyoda-ku, Tokyo, Japan; 22nd Department of Ophthalmology, Toho University School of Medicine, Tokyo, JapanIntroduction: Travoprost 0.004 ...
Inoue K   +5 more
doaj  

Trends in the design and use of elastin-like recombinamers as biomaterials [PDF]

open access: yes, 2019
Producción CientíficaElastin-like recombinamers (ELRs), which derive from one of the repetitive domains found in natural elastin, have been intensively studied in the last few years from several points of view.
Acosta Rodríguez, Sergio   +3 more
core   +2 more sources

Liposomes as sustainable delivery systems in food, cosmetic, and pharmaceutical applications

open access: yesJournal of the American Oil Chemists' Society, Volume 102, Issue 3, Page 547-568, March 2025.
Overview of liposome preparation methods and applications. Abstract Liposomes are artificial microscopic vesicles composed of phospholipid bilayers with the ability to encapsulate both hydrophobic and hydrophilic molecules, owing to the amphipathic nature of lipids.
Minfang Luo   +5 more
wiley   +1 more source

Microscale Delivery Systems for Hydrophilic Active Ingredients in Functional Consumer Goods

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 2, March/April 2025.
Understanding hydrophilic active ingredients by harnessing microscale delivery systems to enhance delivery, precision, efficacy, and shelf life of consumer goods, propelling us toward a sustainable circular economy. ABSTRACT Hydrophilic active ingredients play a crucial role in formulated consumer products, encompassing antioxidants, flavoring ...
Zhirui Guan   +3 more
wiley   +1 more source

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