Multicomponent pharmaceutical products, particularly fixed‐dose combinations (FDCs), have become increasingly important in modern therapeutics to improve patient adherence and therapeutic outcomes. Although chromatographic techniques are widely employed for their analysis, ultraviolet‐visible (UV‐Vis) spectrophotometry remains an attractive alternative
Imad Osman Abu Reid +1 more
wiley +1 more source
Topical timolol for treatment of persistent granulation tissue in the setting of severe hidradenitis suppurativa [PDF]
Hidradenitis suppurativa (HS) is a potentially debilitating dermatological disease that negatively impacts patients' quality of life. Severe cases can be further complicated by persistent granulation tissue at the ostia of sinus tracts, which may prove ...
Chen, Xizhao, Guffey, Darren J
core
Penetration enhancers in ocular drug delivery [PDF]
There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science.
Abdulrazik +38 more
core +1 more source
Early Optic Nerve Symptoms in Neurosarcoidosis: A Clinical Case Review
ABSTRACT Neurosarcoidosis is a rare and often misdiagnosed condition. It should be considered in patients with unexplained neurological symptoms, especially when associated with systemic inflammatory findings. Early diagnosis and immunosuppressive therapy are crucial to prevent irreversible neurological damage.
Isabella Passarelli Giabardo Marques +7 more
wiley +1 more source
Follow-up study of over three years of patients with uveitis after cataract phacoemulsification: outcomes and complications [PDF]
Purpose: To evaluate the rate and onset of intraoperative and postoperative complications post-phacoemulsification. Methods: One hundred sixty-two eyes of 145 patients with uveitis who underwent phacoemulsification between 2006 and 2009 were identified
ABBOUDA, ALESSANDRO +5 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
Kenji Inoue,1 Ryoko Okayama,1 Risako Higa,1 Goji Tomita2 1Inouye Eye Hospital, Tokyo, 2Second Department of Ophthalmology, Toho University School of Medicine, Tokyo, Japan Purpose: We prospectively investigated the intraocular pressure (IOP)-reducing ...
Inoue K, Okayama R, Higa R, Tomita G
doaj
Topical Treatment for Orbital Capillary Hemangioma in an Adult Using a β-Blocker Solution
Purpose: To report a case of orbital capillary hemangioma in an adult who was successfully treated with topical timolol maleate 0.5% solution. Methods: Case report.
Ken Ohnishi +3 more
doaj +1 more source
Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma. [PDF]
PURPOSE. To evaluate the effect of the timolol-dorzolamide fixed combination (TDFC) and latanoprost 0.005% on 24-hour intraocular pressure (IOP), systolic (SBP) and diastolic (DBP) blood pressure, and diastolic ocular perfusion pressure (DOPP) in ...
Floriani I. +4 more
core +1 more source
Stimuli‐responsive systems: A focus on controlled drug delivery for posterior segment ocular disease
This review highlights recent advances in stimuli‐responsive drug delivery for posterior segment diseases, focusing on mechanisms and potential. It also explores mechanically interlocked molecules and bioorthogonal reactions as novel approaches. Challenges and future perspectives are discussed, aiming to bridge the gap between research and clinical ...
Chengzhi Zhang +11 more
wiley +1 more source

