Results 191 to 200 of about 191,310 (286)

Interleukin-16 upregulates tissue inhibitor of metalloproteinase 3 to promote atherosclerotic plaque stability. [PDF]

J Transl Med
He H, Ding M, Zhu Y, Jiang T, Dong D, Xu X, Yu W, Ou H.   +7 more
europepmc   +1 more source

Identification of miR‐150‐5p in Human Amniotic Membrane Mesenchymal Cell‐Derived Extracellular Vesicles as a Novel Mechanism Driving Cardioprotection

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Human amniotic membrane mesenchymal stem cells (hAMSCs) provide significant cardioprotection following myocardial ischemia/reperfusion injury. They improve cardiac function and reduce fibrosis by modulating the MIAT/miR‐150‐5p/HOXA4 signalling axis.
Nunzio Alcharani, Laura Tesoro, Javier Díez‐Mata, José Luis Zamorano, Marta Saura, Maite Iglesias, Carlos Zaragoza   +6 more
wiley   +1 more source

Abnormal Trophoblast Invasion in Early-Onset Preeclampsia: The Involvement of Cystathionine β-Synthase, Specificity Protein 1 and microRNA-22. [PDF]

Cureus
Arora P, Kalra S, Dhingra R, Kshetrapal P, Bhatla N, Dwivedi S.   +5 more
europepmc   +1 more source

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini, Lei Bao, Krishan D. Chhiba, Jing Li, Yulu Wang, Haley Gainer, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Fei Li Kuang, Kyle T. Amber   +10 more
wiley   +1 more source

LncRNA KCNQ1OT1 aggravates myocardial ischemia/reperfusion injury by mediating the EZH2/TIMP-3 axis. [PDF]

Korean J Physiol Pharmacol
Xing Z, Shajidan A, Palida A, Wang Y, Lv M, Gao Y.   +5 more
europepmc   +1 more source

Maintenance Debridement in Chronic Hard‐to‐Heal Wounds: Toward Dynamic Homeostasis and Precision Intervention

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Debridement is widely used across various wound types, but its biological significance differs fundamentally between acute and chronic hard‐to‐heal wounds. In acute wounds, debridement directly triggers the initiation of regeneration; however, in chronic wounds, persistent biofilm, insufficient angiogenesis and dysregulated inflammation lead ...
RuoDi Lu, Yi Zhang, Biao Cheng
wiley   +1 more source

Evaluating the effect of minimal TIMP variants on protecting and transport across the rat brain microvascular cells (RBMEC). [PDF]

Sci Rep
Taheri E, Raeeszadeh-Sarmazdeh M.
europepmc   +1 more source

AP‐1‐Targeting Decoy Oligonucleotides: Mechanisms and Therapeutic Potential as Modulators of Inflammatory Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Numerous cellular functions, such as apoptosis, proliferation, differentiation, survival, transformation and cell migration, are regulated by a crucial transcription factor called activator protein 1 (AP‐1). Growing evidence indicates that AP‐1 is involved in severe conditions like fibrosis, cancer, and organ damage, as well as inflammatory ...
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Vasily N. Sukhorukov, Amin Jalili, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Inflammatory profile of diabetic ketoacidosis in children with type 1 diabetes. [PDF]

BMJ Open Diabetes Res Care
Chaffin Z, Ghetti S, Tancredi D, Rewers A, Rewers M, Gilles S, Ander B, Glaser N.   +7 more
europepmc   +1 more source

Unveiling the Molecular Mechanism of Intestinal Metabolite para‐Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Here we investigated the effect of p‐Cresol on different brain‐cell types to speculate on their specific contribution to autism spectrum disorder (ASD) synaptic dysfunctions. Our in vitro data show that p‐Cresol impairs dendritic arborization and length, disrupts the excitatory/inhibitory balance, and induces glial activation and inflammatory responses.
Wenjie Liao, Kristy Antonioni, Federica Silvestri, Monica Piemontese, Martina Bodria, Eleonora Daini, Antonio M. Persico, Michele Zoli, Andreas M. Grabrucker, Antonietta Vilella   +9 more
wiley   +1 more source